51cg

Biography

Since 2021: Senior Lecturer in Fungal Genetics; School of Medicine, Medical Sciences & Nutrition; 51cg, UK

2013-2021: Lecturer in Molecular Cell Biology; School of Medicine, Medical Sciences & Nutrition; 51cg, UK

2007-2013: Postdoctoral Research Associate at the Department of Biochemistry, University of Oxford, UK

2005-2007: Erwin Schrödinger-Fellow of the Austrian Science Fund (FWF) researching at the Department of Biochemistry, University of Oxford, UK

2003-2005: Postdoctoral Research Associate at the Department of Chromosome Biology, University of Vienna, Austria

1992-2003: Studying Botany and Genetics at the University of Vienna, Austria and at the University of Cologne, Germany

Research Overview

Past Research

Pelletier C, Shaw S, Alsayegh S, Brown AJP, Lorenz A (2024) Candida auris undergoes adhesin-dependent and -independent cellular aggregation. - PLoS Pathogens 20 (3): e1012076 (27pp.)

Bravo Ruiz G, Ross ZK, Gow NAR, Lorenz A (2020) Pseudohyphal growth of the emerging pathogen Candida auris is triggered by genotoxic stress through the S phase checkpoint. - mSphere 5 (2): e00151-20 (17pp.)

Brown SD*, Mpaulo SJ*, Asogwa MN, Jézéquel M, Whitby MC, Lorenz A (2019) DNA sequence differences are determinants of meiotic recombination outcome. - Scientific Reports 9: 16446 (10pp.) (*these authors contributed equally)

Bravo Ruiz G, Ross ZK, Holmes E, Schelenz S, Gow NAR, Lorenz A (2019) Rapid and extensive karyotype diversification in haploid clinical Candida auris isolates. - Current Genetics 65 (5): 1217-1228

Lorenz A, Mehats A, Osman F, Whitby MC (2014) Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombination. - Nucleic Acids Research 42 (22): 13723-13735

Lorenz A, Osman F, Sun W, Nandi S, Steinacher R, Whitby MC (2012) The fission yeast FANCM ortholog directs non-crossover recombination during meiosis. - Science (New York, N.Y.) 336 (6088): 1585-1588

Collaborations

Professor , Graduate School of Science, Tokyo Metropolitan University, Japan 

Dr Takashi Kubota, The Institute of Medical Sciences, 51cg, UK

Professor , Wellcome Trust Centre for Cell Biology, University of Edinburgh, UK

Dr Hajime Murakami, The Institute of Medical Sciences, 51cg, UK

Professor , Department of Biochemistry, University of Oxford, UK

Funding and Grants

02/2020-09/2020: Seed Corn Fund (with Prof Neil Vargesson) - Institutional Strategic Support Fund, Wellcome Trust

10/2019-10/2022: Award for a 3-year PhD-studentship - Kuwait Cultural Office UK, Ministry of Higher Education, Kuwait

10/2019-10/2022: MRC-CMM award for a 3-year PhD-studentship (with Profs Al Brown & Neil Gow) - MRC & 51cg, UK

02/2019-07/2019: Research Incentive Grant - The Carnegie Trust for the Universities of Scotland

07/2018-01/2020: Seed Award in Science - Wellcome Trust

01/2018-01/2019: Research Grant - Tenovus Scotland (with Prof Neil Gow)

10/2017-10/2020: MRC-CMM award for a 3-year PhD-studentship (with Prof Neil Gow) - MRC & 51cg, UK

10/2017-10/2021: IMS award for a 4-year PhD-studentship (with Prof Neil Gow) - 51cg, UK

10/2017-10/2021: EastBio-DTP awards for two 4-year PhD-studentships (with Prof Adele Marston, University of Edinburgh) - BBSRC

06/2017-11/2017: Seed Corn Fund (with Prof Neil Gow) - Institutional Strategic Support Fund, Wellcome Trust

04/2017: One-off Meeting sponsorship (with Dr Isabelle Colas) for the 9th British Meiosis Meeting in Dundee - Genetics Society UK

06/2016-08/2016: G&D Summer studentship (for Ki Choi CHAN, University of York) - Genetics Society UK

01/2015-09/2015: Research Incentive Grant - The Carnegie Trust for the Universities of Scotland

10/2014-10/2015: Research Grant - Royal Society

10/2013-10/2017: DTG award for a 4-year PhD-studentship - BBSRC & 51cg, UK

09/2013: Principal’s Excellence Fund - 51cg

07/2005-07/2007: Erwin Schrödinger-Fellowship - Austrian Science Fund (FWF)

10/1997-06/1998: ERASMUS/SOCRATES-scholarship - European Union

Teaching Responsibilities

Undergraduate Degree Co-ordination

BSc Molecular and Cellular Biology

BSc Biotechnology

BSc Microbiology

Course Co-ordination

GN3502 - Genetics

MB3006 - Molecular Biology of the Cell

Lecturing

MB3006 - Molecular Biology of the Cell: 'Cell Cycle & Cell Division' (Lectures, Tutorial)

GN3502 - Genetics: 'Mendelian Genetics', 'Chromosome Biology', 'Fungal Genetics', 'Genetic Engineering' (Lectures)

MC3504 - Molecular Microbiology: 'Fungal Genetics and Biology' (Lectures)

MB4050 - Genome Organisation and Analysis: 'Genome Integrity - DNA Repair, Homologous Recombination, and Meiosis' (Lectures)

Practicals & Workshops

BI20M3 - Molecular Biology of the Gene: 'Restriction Analysis of DNA'

GN3502 - Genetics: 'Analysis of Meiotic Recombination'

GN3502 - Genetics: 'Pedigree Analysis'

Student Supervision

MB4502 - 'Molecular Biology Honours Research Project'

MB5904 - 'Masters Research Project'

Currently, co-supervisor of two PhD students.

Non-course Teaching Responsibilities

Personal Tutor for 7 UG students in various degree programmes and at all levels

Member of 9-months and 24-months PhD student assessment panels