51cg

People

Dr Andrew Angel

Dr Andrew Angel
Dr Andrew Angel
Dr Andrew Angel

Senior Lecturer

Accepting PhDs

51cg
Email Address
andrew.angel@abdn.ac.uk
Office Address
339 Meston Building
Old Aberdeen Campus
Meston Walk
AB24 3UE

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School/Department
School of Natural and Computing Sciences

Latest Publications

  • Nucleotide resolution 4-thiouridine sequencing by SNU-Seq and sf4sU-Seq reveals the transcriptional responsiveness of an epigenetically primed human genome

    Gerlevik, U., Lorenz, P., Lamstaes, A., Fischl, H., Xi, S., Saukko-Paavola, A., Murray, S. C., Brown, T., Welch, A., George, C., Angel, A., Furger, A., Mellor, J.
    Nucleic Acids Research, vol. 54, no. 12, gkag652
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Spt4 facilitates the movement of RNA polymerase II through the +2 nucleosomal barrier

    Uzun, U., Brown, T., Fishcl, H., Angel, A., Mellor, J.
    Cell Reports, vol. 36, no. 13, pp. 4064-4075
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner

    Jeronimo, C., Angel, A., Nguyen, V. Q., Kim, J. M., Poitras, C., Lambert, E., Collin, P., Mellor, J., Wu, C., Robert, F.
    Molecular Cell, vol. 81, no. 17, pp. 3542-3559.e11
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Global and Gene-specific Transcriptional Responses to Acute Stress

    Fishcl, H., Brown, T., Angel, A., Mellor, J.
    Working Papers: Preprint Papers
    • [ONLINE] DOI:

  • Mapping Human Transient Transcriptomes Using Single Nucleotide Resolution 4sU Sequencing (SNU-Seq)

    Lorenz, P., Lamstaes, A., Fishcl, H., Xi, S., Saukko-Paavola, A., Murray, S. C., Brown, T., George, C., Furger, A., Angel, A., Mellor, J.
    Working Papers: Preprint Papers
    • [ONLINE] DOI:

View My Publications

Research

Research Overview

I am a mathematical modeller of complex biological systems. I apply techniques from statistical physics, mathematics and computer science in order to elucidate the mechanisms that underpin the basic building blocks of life.

Often applying stochastic modelling to systems of interacting biological components, I currently focus on transcription and related areas including chromatin, nucleosome chaperoning and metabolic cycling.

Research Areas

Accepting PhDs

I am currently accepting PhDs in Physics.

Please get in touch if you would like to discuss your research ideas further.

Physics

  • Accepting PhDs
View Research Area

Research Specialisms

  • Molecular Biology
  • Mathematical Modelling
  • Applied Physics

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is , published under the licence.

Current Research

Gene Expression and Transcription in the Yeast Metabolic Cycle

Modelling the Complex Dynamics of Polymerase II Transcription

Modelling the Chaperoning of Nucleosomes During Transcription

Improving the Quantitative Analysis of ChIP-seq Data

Past Research

Modelling Antisense Transcription

Modelling the Epigenetics of Vernalization

Collaborations

Professor Jane Mellor, University of Oxford

Transcription, Chromatin and the Yeast Metabolic Cycle

 

Professor Francois Robert, IRCM Montreal

Transcription through nucleosomes

 

Dr Michael Tellier, University of Leicester

Analysis of ChIP-seq data

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