RNutr
Advanced Research Fellow
- 51cg
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- Email Address
- fiona.campbell@abdn.ac.uk
- Telephone Number
- +44 (0)1224 438617
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
I am a principal investigator based at the Rowett Institute and coordinator of the PGT Human Nutrition MSc programme. My research focuses on advanced glycation end-products (AGEs) in the diet. During food processing AGEs are formed as the result of the Maillard reaction and are absorbed by the body during digestion. To investigate how dietary AGEs, contribute to diet induced conditions such as type 2 diabetes and dementia we are using human intervention studies to test the effects of highly processed foods high in AGEs on sensitive measures of metabolic health and cognition. I am also researching the role of processing methods in improving food quality and the potential for phytochemicals incorporated into processed foods to ameliorate negative health outcomes.
Qualifications
- B.Sc. (Hons.) Biochemistry1985 - 51cg
- Ph.D. Biomedical Science and Nutrition1998 - 51cg
Thesis Title: 'Long-chain Fatty Acid Transport by the Human Placenta: The Role of Fatty Acid-Binding Proteins'
External Memberships
Registered Nutritionist with the AfN (RNutr)
Member of the Nutrition Society,
Member of Biochemical Society,
Member of British Society for Proteome Resarch (BSPR).
Latest Publications
Selenium Supplementation in Pregnancy-Maternal and Newborn Outcomes
Journal of Nutrition and Metabolism, vol. 2022, 4715965Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction
Molecular Nutrition & Food Research, vol. 65, no. 1, 1900934Contributions to Journals: Review articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin
Journal of Functional Foods, vol. 64, 103597Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
Cinnamon Shows Antidiabetic Properties that Are Species-Specific: Effects on Enzyme Activity Inhibition and Starch Digestion
Plant Foods for Human Nutrition, vol. 74, no. 4, pp. 544-552Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
Early and reversible changes to the hippocampal proteome in mice on a high-fat diet
Nutrition and Metabolism, vol. 16, no. 1, 57Contributions to Journals: Articles- [ONLINE]
- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
- [ONLINE]
- Research
-
Research Overview
A high-fat/sugar diet leads to the formation of Advanced Glycation End products (AGEs) in body tissues. AGEs cause damage and inflammation and are also absorbed from the diet particularly from processed foods. We are interested in how dietary AGEs contribute to diet induced conditions such as type 2 diabetes and cognitive decline.
Current Research
- The role of specific components of the Western diet, namely advanced glycation end products (AGEs), in metabolic health and the development of chronic diseases.
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Key interests include studying the effects of foods containing high levels of AGEs on metabolic health, the potential of phytochemicals to prevent diseases, improving food quality through processing methods, and reformulating processed foods with plant bio-actives.
- Principal investigator for nutrition research studies and leading a Scottish Government (RESAS), funded human intervention study that compares the health benefits of consuming soft fruits. .,
Past Research
- Principal investigator for nutrition research studies and leading a Scottish Government (RESAS), funded human intervention study that compares the health benefits of consuming soft fruits. ., .
- Teaching
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Teaching Responsibilities
- Programme lead for the Association of Nutrition (AfN) accredited MSc Human Nutrition programme at the 51cg (2020- present). Ensure compliance with AfN standards and academic standards set by the University.
- Coordinator of RN5003Foundations of Nutrition course (2020-present)
- Coordinator for on-line course Fundamentals of Nutrition RN5001(2017-present)
- Postgraduate Exam Officer for School of Medicine Medical Sciences and Nutrition
- Publications
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Page 1 of 1 Results 1 to 64 of 64
Selenium Supplementation in Pregnancy-Maternal and Newborn Outcomes
Journal of Nutrition and Metabolism, vol. 2022, 4715965Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
The Role of Dietary Advanced Glycation End Products in Metabolic Dysfunction
Molecular Nutrition & Food Research, vol. 65, no. 1, 1900934Contributions to Journals: Review articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin
Journal of Functional Foods, vol. 64, 103597Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
Cinnamon Shows Antidiabetic Properties that Are Species-Specific: Effects on Enzyme Activity Inhibition and Starch Digestion
Plant Foods for Human Nutrition, vol. 74, no. 4, pp. 544-552Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
Early and reversible changes to the hippocampal proteome in mice on a high-fat diet
Nutrition and Metabolism, vol. 16, no. 1, 57Contributions to Journals: Articles- [ONLINE]
- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
- [ONLINE]
A high-fat diet induces rapid changes in the mouse hypothalamic proteome
Nutrition and Metabolism, vol. 16, 26Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
- [ONLINE]
- [ONLINE]
- [ONLINE]
Do advanced glycation end products contribute to saturated fat induced inflammation?
Proceedings of the Nutrition Society, vol. 78, no. OCE1, E42Contributions to Journals: Abstracts- [ONLINE] DOI:
- [ONLINE]
SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice
Genes & Nutrition, vol. 13, 28Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Hippocampal proteomics and primary cell cultures demonstrate proteins key in neuronal plasticity are rapidly changed in rodents on a high-fat diet
onference: Society for Neuroscience 2018Contributions to Conferences: AbstractsRapid and reversible impairment of episodic memory by a high-fat diet in mice
Scientific Reports, vol. 8, 11976Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Beetroot improves oxidative stability and functional properties of processed foods: singular and combined effects with chocolate
Journal of Food Science and Technology, vol. 55, no. 7, pp. 2401-2409Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Having your cake and eating it? The impact of Beetroot addition on the Nutrition, oxidative stability and Quality of cake
The Nutrition Society Summer Meeting 2016, E108Contributions to Journals: Abstracts- [ONLINE] DOI:
Breads fortified with freeze-dried vegetables: Quality and nutritional attributes. part ii: Breads not containing oil as an ingredient
Foods, vol. 5, no. 3, pp. 1-14Contributions to Journals: Articles- [ONLINE] DOI:
- [ONLINE]
Breads Fortified with Freeze-Dried Vegetables: Quality and Nutritional Attributes. Part II: Breads Not Containing Oil as an Ingredient
Foods, vol. 5, no. 3, pp. 1-14Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Breads Fortified with Freeze-Dried Vegetables: Quality and Nutritional Attributes. Part 1: Breads Containing Oil as an Ingredient
Foods, vol. 5, no. 1, pp. 1-13Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
A novel hypothalamic protein regulated by high fat diet and leptin
Proceedings of the Nutrition Society, vol. 74, no. OCE3, pp. E190Contributions to Journals: Abstracts- [ONLINE] DOI:
The development of diet-induced obesity and glucose intolerance in C57BL/6 mice on a high-fat diet consists of distinct phases
PloS ONE, vol. 9, no. 8, e106159Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Antioxidant effectiveness of vegetable powders on the lipid and protein oxidative stability of cooked Turkey meat patties: implications for health
Nutrients, vol. 5, no. 4, pp. 1241-1252Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Decrease in plasma protein markers of oxidative stress and inflammation in overweight/obese type 2 diabetics after supplementation with bilberry extract
Obesity Facts, vol. 5, no. S1, pp. 198-199Contributions to Journals: Abstracts- [ONLINE] DOI:
Lower levels of damaged protein biomarkers in the plasma of overweight type 2 diabetic men following supplementation with a standardised bilberry extract
Proceedings of the Nutrition Society, vol. 71, no. OCE2, pp. E130Contributions to Journals: Abstracts- [ONLINE] DOI:
- [OPEN ACCESS]
Proteomics reveals that a high-fat diet induces rapid changes in hypothalamic proteins related to neuronal damage and inflammation
Proceedings of the Nutrition Society, vol. 70, no. OCE6, pp. E370Contributions to Journals: Abstracts- [ONLINE] DOI:
- [OPEN ACCESS]
High-Fat Diet in C57Bl/6 Mice Induces a Rapid Decrease in Insulin Sensitivity and an Acute Phase Response
Endocrine Reviews, vol. 32, no. 03_MeetingAbstracts, pp. 1-483Contributions to Journals: Articles- [ONLINE]
Identification of Plasma Protein Markers of Oxidation in Obese Men
biochemical society focussed meetingContributions to Conferences: Posters- [ONLINE]
Optimal combinations of acute phase proteins for detecting infectious disease in pigs
Veterinary Research, vol. 42, pp. 50Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Identification of damaged proteins in human serum using modified Ehrlich's reagent to target protein-bound pyrroles
Analytical Biochemistry, vol. 398, no. 1, pp. 76-82Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Rapid and widely disseminated acute phase protein response after experimental bacterial infection of pigs
Veterinary Research, vol. 40, no. 3, 23Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
SERRS immunoassay for quantitative human CRP analysis
Analyst, vol. 133, no. 10, pp. 1355-1357Contributions to Journals: Articles- [ONLINE] DOI:
The association between plasma levels of acute phase proteins, haptoglobin, alpha-1 acid glycoprotein (AGP), Pig-MAP, transthyretin and serum amyloid A (SAA) in Large White and Meishan pigs
Veterinary Immunology and Immunopathology, vol. 119, no. 3-4, pp. 303-309Contributions to Journals: Articles- [ONLINE] DOI:
Effects of sub-clinical post-weaning colibacillosis and dietary protein on acute phase proteins in weaner pigs
Livestock Science , vol. 108, no. 1-3, pp. 182-185Contributions to Journals: Articles- [ONLINE] DOI:
A time-resolved immunofluorometric assay for porcine C-reactive protein quantification in whole blood
Luminescence, vol. 22, no. 3, pp. 171-176Contributions to Journals: Articles- [ONLINE] DOI:
Characterisation of the pig acute phase protein response to road transport
Veterinary Journal, vol. 173, no. 3, pp. 669-674Contributions to Journals: Articles- [ONLINE] DOI:
Pig acute-phase protein levels after stress induced by changes in the pattern of food administration
Animal , vol. 1, no. 1, pp. 133-139Contributions to Journals: Articles- [ONLINE] DOI:
The porcine acute phase protein response to acute clinical and subclinical experimental infection with Streptococcus suis
Veterinary Immunology and Immunopathology, vol. 113, no. 1-2, pp. 157-168Contributions to Journals: Articles- [ONLINE] DOI:
The welfare of finishing pigs in two contrasting housing systems: Fully-slatted versus straw-bedded accommodation
Livestock Production Science, vol. 103, no. 1-2, pp. 104-115Contributions to Journals: Articles- [ONLINE] DOI:
The negative acute phase response of serum transthyretin following Streptococcus suis infection in the pig
Veterinary Research, vol. 36, no. 4, pp. 657-664Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Relative importance of malonyl CoA and carnitine in maturation of fatty acid oxidation in newborn rabbit heart
American Journal of Physiology, Heart and Circulatory Physiology, vol. 284, no. 1, pp. H283-H289Contributions to Journals: Articles- [ONLINE] DOI:
45. Acute phase proteins: Biomarkers for use in animal health & welfare and in food quality & safety
Research in Veterinary Science, vol. 74, no. Supplement 1Contributions to Journals: AbstractsMonitoring the innate immune response with acute phase protein
SPVS Bulletin, pp. 39-41Contributions to Journals: Literature ReviewsArachidonic acid stimulates internalisation of leptin by human placental choriocarcinoma (BeWo) cells
Biochemical and Biophysical Research Communications, vol. 299, no. 3, pp. 432-437Contributions to Journals: Articles- [ONLINE] DOI:
A role for peroxisome proliferator-activated receptor alpha (PPAR alpha) in the control of cardiac malonyl-CoA levels: REDUCED FATTY ACID OXIDATION RATES AND INCREASED GLUCOSE OXIDATION RATES IN THE HEARTS OF MICE LACKING PPARa ARE ASSOCIATED WITH HIGHER CONCENTRATIONS OF MALONYL-CoA AND REDUCED EXPRESSION OF MALONYL-CoA DECARBOXYLASEREDUCED FATTY ACID OXIDATION RATES AND INCREASED GLUCOSE OXIDATION RATES IN THE HEARTS OF MICE LACKING PPARa ARE ASSOCIATED WITH HIGHER CONCENTRATIONS OF MALONYL-CoA AND REDUCED EXPRESSION OF MALONYL-CoA DECARBOXYLASE
The Journal of Biological Chemistry, vol. 277, no. 6, pp. 4098-4103Contributions to Journals: Articles- [ONLINE] DOI:
Low fatty acid oxidation rates in isolated working hearts from PPAR alpha null mice does not impair functional recovery following ischemia
Diabetes, vol. 50, no. Suppl. 2, pp. A308-A309Contributions to Journals: ArticlesPPAR alpha regulates cardiac energy metabolism by controlling malonyl CoA concentrations in the heart
Journal of Molecular and Cellular Cardiology, vol. 33, no. 6, pp. A164Contributions to Journals: Articles- [ONLINE] DOI:
Preferential distribution of long chain polyunsaturated fatty acids in phospatidyl ethanolamine fraction of Guinea pig alveolar apical membranes
Prostaglandins, Leukotrienes and Essential Fatty Acids, vol. 62, no. 6, pp. 341-348Contributions to Journals: Articles- [ONLINE] DOI:
Immunological manipulation of lactation
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsDifferential distribution and metabolism of arachidonic acid and docosahexaenoic acid by human placental choriocarcinoma (BeWo) cells
Molecular & Cellular Biochemistry, vol. 185, no. 1-2, pp. 191-198Contributions to Journals: Articles- [ONLINE] DOI:
Detection and cellular localization of plasma membrane-associated and cytoplasmic fatty acid-binding proteins in human placenta
Placenta, vol. 19, no. 5-6, pp. 409-415Contributions to Journals: Articles- [ONLINE] DOI:
Interaction of free fatty acids with human leptin
Biochemical and Biophysical Research Communications, vol. 247, no. 3, pp. 654-658Contributions to Journals: ArticlesPlacental membrane fatty acid-binding protein preferentially binds arachidonic and docosahexaenoic acids
Life Sciences, vol. 63, no. 4, pp. 235-240Contributions to Journals: Articles- [ONLINE] DOI:
Preferential uptake of long-chain polyunsaturated fatty acids by human placental cells
Chapters in Books, Reports and Conference Proceedings: Conference ProceedingsUptake of long chain fatty acids by human placental choriocarcinoma (BeWo) cells
Journal of Lipid Research, vol. 38, no. 12, pp. 2558-2568Contributions to Journals: Articlesalpha-Tocopherol-binding protein in the cytosol of the human placenta
Biochemical Society Transactions, vol. 24, no. 2, pp. 202SContributions to Journals: ArticlesAsymmetric distribution of the plasma membrane fatty acid-binding protein (FABPpm) in the human placenta
Biochemical Society Transactions, vol. 24, no. 2, pp. 249SContributions to Journals: ArticlesPlatelet membrane glycoprotein IV (CD36) is involved in arachidonic acid induced-platelet aggregation
Biochemical Society Transactions, vol. 24, no. 2, pp. 167SContributions to Journals: ArticlesPreferential uptake of long chain polyunsaturated fatty acids by isolated human placental membranes
Molecular & Cellular Biochemistry, vol. 155, no. 1, pp. 77-83Contributions to Journals: Articles- [ONLINE] DOI:
Arachidonic acid uptake by human platelets is mediated by CD36
Platelets, vol. 7, no. 5-6, pp. 291-295Contributions to Journals: ArticlesPlasma-membrane fatty-acid-binding protein (FABP(PM)) is exclusively located in the maternal facing membranes of the human placenta
FEBS Letters, vol. 375, no. 3, pp. 227-230Contributions to Journals: Articles- [ONLINE] DOI:
Plasma-membrane fatty-acid-binding protein in human placenta-identification and characterization
Biochemical and Biophysical Research Communications, vol. 209, no. 3, pp. 1011-1017Contributions to Journals: Articles- [ONLINE] DOI:
Characterization of a novel alpha-tocopherol-binding-protein from bovine heart cytosol
Archives of Biochemistry and Biophysics, vol. 318, no. 1, pp. 140-146Contributions to Journals: Articles- [ONLINE] DOI:
Vitamin-E requirements, transport, and metabolism: role of alpha-tocopherol-binding proteins
The Journal of Nutritional Biochemistry, vol. 5, no. 12, pp. 562-570Contributions to Journals: Literature Reviews- [ONLINE] DOI:
Plasma-membrane fatty-acid-binding protein (FABP(PM)) of the sheep placenta
Biochimica et Biophysica Acta - Lipids and Lipid Metabolism, vol. 1214, no. 2, pp. 187-192Contributions to Journals: Articles- [ONLINE] DOI:
Identification and partial characterization of Fatty-Acid-Binding Sites in Sheep Placental Membranes
Biochemical Society Transactions, vol. 22, no. 2, pp. S117Contributions to Journals: ArticlesIdentification of a low molecular mass (14.2 kDa) a-tocopherol-binding protein in the cytosol of rat liver and heart
Biochemical and Biophysical Research Communications, vol. 196, no. 3, pp. 1108-1112Contributions to Journals: Articles- [ONLINE] DOI:
A low molecular weight (12-15kDa) protein fraction in rat liver binds alpha-tocopherol
Biochemical Society Transactions, vol. 21, no. 4, pp. 408SContributions to Journals: Abstracts- [ONLINE] DOI:
Alpha-Tocopherol-Binding Protein in Bovine Heart Cytosol
The FASEB Journal, vol. 7, no. 3Contributions to Journals: Abstracts