51cg

People

Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

51cg
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the 51cg, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - 51cg 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available  on using instrumental variables in a surgery trial to address non-compliance. Collaborators were  (Oxford), (Lancaster), and (Manchester). 

Research on making trials more efficient, collaborating with . 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • The UK resuscitative endovascular balloon occlusion of the aorta in trauma patients with life-threatening torso haemorrhage: The (UK-REBOA) multicentre RCT

    Jansen, J. O., Hudson, J., Kennedy, C., Cochran, C., Maclennan, G., Gillies, K., Lendrum, R., Sadek, S., Boyers, D., Ferry, G., Lawrie, L., Nath, M., Cotton, S., Wileman, S., Forrest, M., Brohi, K., Harris, T., Lecky, F., Moran, C., Morrison, J. J., Norrie, J., Paterson, A., Tai, N., Welch, N., Campbell, M. K., UK-REBOA Study Group
    Health Technology Assessment, vol. 28, no. 54
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Public perspective on potential treatment intervention harm in clinical trials-terminology and communication

    Phillips, R., Bi, D., Goulão, B., Miller, M., El-Askary, M., Fagbemi, O., Freeborn, C., Giammetta, M., El Masri, N., Flockhart, P., Kumar, M., Melvin, M., Murray, D., Myhill, A., Saeid, L., Thomas, S., MacLennan, G., Cornelius, V.
    Trials, vol. 25, no. 1, 573
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Feasibility of in-home monitoring for people with glaucoma: the I-TRAC mixed-methods study

    Stewart, C., Wu, H., Alagappan, U., Azuara-Blanco, A., King, A. J., Tatham, A. J., Hernández, R., Lowe, B., Shotton, D., Appiah, N., Coffey, T., Vadiveloo, T., MacLennan, G., Gillies, K.
    Health technology assessment (Winchester, England), vol. 28, no. 44, pp. 1-163
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Text Messages With Financial Incentives for Men With Obesity: A Randomized Clinical Trial

    Hoddinott, P., O'Dolan, C., Macaulay, L., Dombrowski, S. U., Swingler, J., Cotton, S., Avenell, A., Getaneh, A. M., Gray, C., Hunt, K., Kee, F., MacLean, A., McKinley, M., Torrens, C., Turner, K., van der Pol, M., MacLennan, G.
    JAMA, vol. 332, no. 1, pp. 31-40
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Evaluating Primary Treatment for People with Advanced Glaucoma: Five-Year Results of the Treatment of Advanced Glaucoma Study

    King, A. J., Hudson, J., Azuara-Blanco, A., Burr, J., Kernohant, A., Homer, T., Shabaninejad, H., Sparrow, J. M., Garway-Heath, D., Barton, K., Norrie, J., Davidson, T., Vale, L., MacLennan, G., TAGS Study Group
    Ophthalmology, vol. 131, no. 7, pp. 759-770
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Assessment of depth of sedation using Bispectral Index™ monitoring in patients with severe traumatic brain injury in UK intensive care units

    Kaye, C., Rhodes, J., Austin, P., Casey, M., Gould, R., Sira, J., Treweek, S., MacLennan, G.
    BJA Open, vol. 10, 100287
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Laparoscopic cholecystectomy versus conservative management for adults with uncomplicated symptomatic gallstones: the C-GALL RCT

    Innes, K., Ahmed, I., Hudson, J., Hernández, R. A., Gillies, K., Bruce, R., Bell, V., Avenell, A., Blazeby, J. M., Brazzelli, M., Cotton, S., Croal, B., Forrest, M., MacLennan, G., Murchie, P., Wileman, S., Ramsay, C.
    Health Technology Assessment, vol. 28, no. 26, pp. 1-151
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial

    Devereux, G., Cotton, S., Nath, M., McMeekin, N., Campbell, K., Chaudhuri, R., Choudhury, G., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J., Lee, A. J., MacLennan, G., Morice, A., Norrie, J., Price, D., Short, P., Vestbo, J., Walker, P., Wedzicha, J., Wilson, A., Wu, O., Lipworth, B. J.
    JAMA, vol. 332, no. 6, pp. 462-470
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Prevalencia del cáncer del tracto urinario. Análisis de la cohorte española del estudio IDENTIFY

    Toribio-Vázquez, C., Gómez Rivas, J., Amigo, F., Carrión, D. M., Yebes, , Alonso-Bartolomé, M., Ayllon, H., Aguilera, A., Martinez-Pineiro, L., Antón-Juanilla, M., Crespo-Atín, V., Otaola-Arca, H., Herranz-Yague, J. A., Munoz Rivero, M. V., MacKenzie, K. R., Shah, T. T., Gao, C., Zimmermann, E., Jefferies, M., Nambiar, A., Gallagher, K. M., Khadhouri, S., Kasivisvanathan, V., Moore, S., Zimmermann, E. F., Edison, E., Mannas, M. P., Lee, T., Marra, G., Lillaz, B., Olivier, J., Assmus, M. A., Uçar, T., Claps, F., Boltri, M., Burnhope, T., Nkwam, N., Tanasescu, G., Boxall, N. E., Downey, A. P., Ahmed Lal, A., Clarke, H., HW Lau, D., Gillams, K., Crockett, M., Nielsen, M., Takwoingi, Y., Chuchu, N., O'Rourke, J., MacLennan, G., IDENTIFY Study group
    Actas Urologicas Espanolas, vol. 48, no. 3, pp. 228-237
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Resuscitative Endovascular Balloon Occlusion of the Aorta in Patients With Exsanguinating Hemorrhage-Reply

    Jansen, J. O., MacLennan, G. S., Campbell, M. K.
    JAMA, vol. 331, no. 11, pp. 981-982
    Contributions to Journals: Comments and Debates
    • [ONLINE] DOI:
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