51cg

Dr MARLENE LORGEN-RITCHIE

Dr MARLENE LORGEN-RITCHIE
Dr MARLENE LORGEN-RITCHIE
Dr MARLENE LORGEN-RITCHIE

BSc, PhD

Research Fellow

51cg

Biography

I completed an undergraduate degree in Marine Biology at the 51cg followed by a PhD investigating the molecular basis of parr-smolt transformation in Atlantic salmon, completed in 2015. I next spent time developing my skills in molecular biology as a post-doc studying tRNA charging in E.coli and yeast using microarray technology at the Institute of Medical Sciences before moving to the Rowett Institute to study epigenetics in relation to adult cognition and mood.

I returned to the School of Biological Sciences in 2019 to take up a position as a research fellow in the Scottish Fish Immunology Research Centre (SFRIC). My research covers topics from genome duplication and rearing system impacts on microbiome compositions, to gill health and novel nutritional sources for fish feeds, working with a range of academic and industry collaborators.

 

Qualifications

  • BSc (Hons) Marine Biology 
    2011 - 51cg 

    1st class

  • PhD Biology 
    2015 - 51cg 

Latest Publications

  • Characterisation of eicosanoid-regulating genes in Atlantic salmon: insights into the control of pro-inflammatory and anti-inflammatory lipid mediators

    Abushweka, A. A., Naseer, S., Holland, J., Lorgen-Ritchie, M., Martin, S.
    Fish & Shellfish Immunology, vol. 173, 111296
    Contributions to Journals: Articles
  • Microbial and histopathological insights into gill health of Atlantic salmon ( Salmo salar ) across Scottish aquaculture sites

    Costelloe, E. P., Lorgen-Ritchie, M., Krol, E., Noguera, P., Bickerdike, R., Tinsley, J., Valdenegro, V., Douglas, A., Martin, S. A.
    Aquaculture, vol. 599, 742166
    Contributions to Journals: Articles
  • Impact of freshwater rearing history on Atlantic salmon (Salmo salar) gill in response to viral stimulation post seawater transfer

    Lorgen-Ritchie, M.
    Contributions to Conferences: Oral Presentations
  • Impact of freshwater rearing history on Atlantic salmon gill response to viral stimulation post seawater transfer

    Lorgen-Ritchie, M., Chalmers, L., Clarkson, M., Taylor, J. F., MacKenzie, S., Migaud, H., Martin, S.
    Fish and Shellfish Immunology, vol. 150, 109653
    Contributions to Journals: Articles
  • Modulation of gut microbiota composition and predicted metabolic capacity after nutritional programming with a plant-rich diet in Atlantic salmon (Salmo salar): insights across developmental stages

    Tawfik, M. M., Lorgen-Ritchie, M., Krol, E., McMillan, S., Norambuena, F., Bolnick, D. I., Douglas, A., Tocher, D. R., Betancor, M. B., Martin, S.
    Animal Microbiome, vol. 6, 38
    Contributions to Journals: Articles

View My Publications

Research

Research Overview

As a post-doctoral fellow in the Scottish Fish Immunology Research Centre (SFIRC) here at the 51cg, my interests target the immunological performance of fish in an aquaculture setting. The aquaculture industry is important in meeting the nutritional needs of our ever-growing world population, but these needs can only be met if the industry grows sustainability, putting fish health and welfare at the forefront. 

Research Areas

Biological and Environmental Sciences

  • Supervising

Research Specialisms

  • Aquaculture
  • Molecular Biology
  • Animal Health
  • Animal Nutrition

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is , published under the licence.

Current Research

My current research focusses on gill health within the Atlantic salmon aquaculture sector, seeking to understand how genetics, environment and gill microbiomes interact in determining gill health and robustness, in partnership with the Institute of Aquaculture at Stirling University.

Past Research

Past research has uncovered neo-functionalization of gene paralogues following a whole-genome duplication event in salmonids, highlighting a potential role for WGD in the range of life history strategies employed by salmonid species.

We have also identified links between rearing system environments and temporal composition of microbiomes across mucosal tissues, both internal and external, in Atlantic salmon, highlighting important considerations for the industry in the adoption of novel husbandry environments with a view to promoting a more ecosystem-conscience and sustainable industry.

Nutrition is another key component in aquaculture. The stagnation or collapse of wild forage fisheries traditionally used to source fishmeal and oils for diet formulations has led to the search for novel ingredients, including plant-based alternatives. However, plants lack the health-boosting omega-3s which salmonids famously provide, but are acquired through their diet. The seed oils of novel plants engineered to produce omega-3s within were shown to bridge the gap between fish- and plant-oil fed salmon in terms of immune transcriptomic profile, and lipid composition in blood plasma.

Funding and Grants

2024-2027 Mitigating salmon gill disease by integrating genotype-environment studies with host-gill microbiome associations BBSRC BB/Y005295/1

2024-2026 The role of photoperiod in immune development and health in salmon aquaculture BBSRC BB/Z515267/1

2024-2026 Camelina omega-3 oil for optimal heart and gill health BBSRC BB/Z515322/1

2024-2024 Developing an Indonesian skills base for sustainable environmental development Scottish Funding Council SF10272-12 

Teaching
Publications

Page 1 of 1 Results 1 to 16 of 16

  • Characterisation of eicosanoid-regulating genes in Atlantic salmon: insights into the control of pro-inflammatory and anti-inflammatory lipid mediators

    Abushweka, A. A., Naseer, S., Holland, J., Lorgen-Ritchie, M., Martin, S.
    Fish & Shellfish Immunology, vol. 173, 111296
    Contributions to Journals: Articles
  • Microbial and histopathological insights into gill health of Atlantic salmon ( Salmo salar ) across Scottish aquaculture sites

    Costelloe, E. P., Lorgen-Ritchie, M., Krol, E., Noguera, P., Bickerdike, R., Tinsley, J., Valdenegro, V., Douglas, A., Martin, S. A.
    Aquaculture, vol. 599, 742166
    Contributions to Journals: Articles
  • Impact of freshwater rearing history on Atlantic salmon (Salmo salar) gill in response to viral stimulation post seawater transfer

    Lorgen-Ritchie, M.
    Contributions to Conferences: Oral Presentations
  • Impact of freshwater rearing history on Atlantic salmon gill response to viral stimulation post seawater transfer

    Lorgen-Ritchie, M., Chalmers, L., Clarkson, M., Taylor, J. F., MacKenzie, S., Migaud, H., Martin, S.
    Fish and Shellfish Immunology, vol. 150, 109653
    Contributions to Journals: Articles
  • Modulation of gut microbiota composition and predicted metabolic capacity after nutritional programming with a plant-rich diet in Atlantic salmon (Salmo salar): insights across developmental stages

    Tawfik, M. M., Lorgen-Ritchie, M., Krol, E., McMillan, S., Norambuena, F., Bolnick, D. I., Douglas, A., Tocher, D. R., Betancor, M. B., Martin, S.
    Animal Microbiome, vol. 6, 38
    Contributions to Journals: Articles
  • Time is a stronger predictor of microbiome community composition than tissue in external mucosal surfaces of Atlantic salmon (Salmo salar) reared in a semi-natural freshwater environment

    Lorgen-Ritchie, M., Chalmers, L., Clarkson, M., Taylor, J. F., Migaud, H., Martin, S. A.
    Aquaculture, vol. 566, 739211
    Contributions to Journals: Articles
  • Microbiomes in the context of developing sustainable intensified aquaculture

    Lorgen-Ritchie, M., Uren Webster, T., McMurtrie, J., Bass, D., Tyler, C. R., Rowley, A., Martin, S. A. M.
    Frontiers in Microbiology, vol. 14, 1200997
    Contributions to Journals: Review articles
  • Temporal changes in skin and gill microbiomes of Atlantic salmon in a recirculating aquaculture system – Why do they matter?

    Lorgen-Ritchie, M., Clarkson, M., Chalmers, L., Taylor, J. F., Migaud, H., Martin, S. A.
    Aquaculture, vol. 558, 738352
    Contributions to Journals: Articles
  • Temporal changes in skin and gill microbiomes re impacted by deviations in the microbial community of rearing water in a recirculating aquaculture system’

    Lorgen-Ritchie, M., Chalmers, L., Clarkson, M., Taylor, J., Migaud, H., Martin, S.
    Contributions to Conferences: Oral Presentations
  • A Temporally Dynamic Gut Microbiome in Atlantic Salmon During Freshwater Recirculating Aquaculture System (RAS) Production and Post-seawater Transfer

    Lorgen-Ritchie, M., Clarkson, M., Chalmers, L., Taylor, J. F., Migaud, H., Martin, S. A. M.
    Frontiers in Marine Science, vol. 8, 869
    Contributions to Journals: Articles
  • Temporal dynamics of the gut microbiome in Atlantic salmon during smolting in an industrial recirculating aquaculture system and following SW transfer

    Lorgen-Ritchie, M.
    Contributions to Conferences: Oral Presentations
  • Imprinting methylation predicts hippocampal volumes and hyperintensities and the change with age in later life

    Ritchie, M., Murray, A., Staff, R., Ferguson-Smith, A. C., Richards, M., Horgan, G. W., Phillips, L., Hoad, G., McNeil, C., Ribeiro, A., Haggarty, P.
    Scientific Reports, vol. 11, 943
    Contributions to Journals: Articles
  • Imprinting methylation in SNRPN and MEST1 in adult blood predicts cognitive ability

    Lorgen-Ritchie, M., Murray, A. D., Ferguson-Smith, A. C., Richards, M., Horgan, G. W., Phillips, L. H., Hoad, G., Gall, I., Harrison, K., McNeill, G., Ito, M., Haggarty, P.
    PloS ONE, vol. 14, no. 2, e0211799
    Contributions to Journals: Articles
  • NFAT5 genes are part of the osmotic regulatory system in Atlantic salmon (Salmo salar)

    Lorgen, M., Jørgensen, E. H., Jordan, W. C., Martin, S. A. M., Hazlerigg, D. G.
    Marine Genomics, vol. 31, pp. 25–31
    Contributions to Journals: Articles
  • Cyclical DNA Methyltransferase 3a Expression Is a Seasonal and Estrus Timer in Reproductive Tissues

    Lynch, E. W. J., Coyle, C. S., Lorgen, M., Campbell, E. M., Bowman, A. S., Stevenson, T. J.
    Endocrinology, vol. 157, no. 6, pp. 2469 –2478
    Contributions to Journals: Articles
  • Functional Divergence of Type 2 Deiodinase Paralogs in the Atlantic Salmon

    Lorgen, M. C., Casadei, E., Król, E., Douglas, A., Birnie, M. J., Ebbesson, L. O. E., Nilsen, T. O., Jordan, W. C., Jørgensen, E. H., Dardente, H., Hazlerigg, D. G., Martin, S. A. M.
    Current Biology, vol. 25, no. 7, pp. 936-941
    Contributions to Journals: Articles

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