51cg

People

Dr Thomas Hiscock

Dr Thomas Hiscock
Dr Thomas Hiscock
Dr Thomas Hiscock

Senior Lecturer

Accepting PhDs

51cg
Email Address
thomas.hiscock@abdn.ac.uk
Telephone Number
+44 (0)1224 437331
Office Address

UNIVERSITY OF ABERDEEN
Institute of Medical Sciences 
School of Medicine, Medical Sciences & Nutrition
Foresterhill Health Campus
ABERDEEN, AB25 2ZD, Scotland, UK

School/Department
School of Medicine, Medical Sciences and Nutrition



Biography

I originally trained as a theoretical physicist at the University of Cambridge (B.A.,M.Sci), before setting off across the Atlantic to do my Ph.D. at Harvard Medical School. In Sean Megason's lab, I fell in love with embryos, and spent the best part of six years watching them develop under a microscope. In my postdoc, supervised by John Marioni and Ben Simons at the University of Cambridge, I worked on several projects combining my training in physics with my love for developmental biology. In Summer 2020, I started as a Lecturer in Systems Biology at the IMS. 

Research

Research Overview

I use mathematical models, computational data analysis and close collaborations with experimentalists to understand development - the remarkable processes that allow single-cell embryos to develop into complex, functional and diverse adult forms. Please see my personal website for more details: 

Research Areas

Accepting PhDs

I am currently accepting PhDs in Maths, Biomedical Sciences, Physics.

Please get in touch if you would like to discuss your research ideas further.

Maths

  • Accepting PhDs
View Research Area

Biomedical Sciences

  • Accepting PhDs
View Research Area

Physics

  • Accepting PhDs
View Research Area

Research Specialisms

  • Mathematical Modelling
  • Developmental Biology

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is , published under the licence.

Teaching

Courses

Publications

Page 1 of 2 Results 1 to 10 of 19

  • Fundamental limits on symmetry breaking by Turing-like activator-inhibitor mechanisms

    Muzatko, D., Daga, B., Hiscock, T.
    Development, vol. 153, no. 16, dev205067
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitors

    Xiong, F., Tentner, A. R., Nandagopal, S., Hiscock, T. W., Huang, P., Tsung-Megason, S. G.
    eLife, vol. 13, RP96980
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Self-organized BMP signaling dynamics underlie the development and evolution of digit segmentation patterns in birds and mammals

    Grall, E., Feregrino, C., Fischer, S., De Courten, A., Sacher, F., Hiscock, T., Tschopp, P.
    Proceedings of the National Academy of Sciences of the United States of America, vol. 121, no. 2, 2304470121
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Secreted inhibitors drive the loss of regeneration competence in Xenopus limbs

    Aztekin, C., Hiscock, T. W., Gurdon, J., Jullien, J., Marioni, J. C., Simons, B. D.
    Development, vol. 148, no. 11, dev199158.
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • A dot-stripe Turing model of joint patterning in the tetrapod limb

    Scoones, J. C., Hiscock, T. W.
    Development, vol. 147, no. 8, dev183699
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • The myeloid lineage is required for the emergence of a regeneration-permissive environment following Xenopus tail amputation

    Aztekin, C., Hiscock, T. W., Butler, R., De Jesús Andino, F., Robert, J., Gurdon, J. B., Jullien, J.
    Development, vol. 147, no. 3, 185496
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Navigating at night: fundamental limits on the sensitivity of radical pair magnetoreception under dim light

    Hiscock, H. G., Hiscock, T. W., Kattnig, D. R., Scrivener, T., Lewis, A. M., Manolopoulos, D. E., Hore, P. J.
    Quarterly reviews of biophysics, vol. 52, e9
    Contributions to Journals: Review articles
    • [ONLINE] DOI:
    • [ONLINE]
    • [ONLINE]

  • Identification of a regeneration-organizing cell in the Xenopus tail

    Aztekin, C., Hiscock, T. W., Marioni, J. C., Gurdon, J. B., Simons, B. D., Jullien, J.
    Science, vol. 364, no. 6441, pp. 653-658
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Adapting machine-learning algorithms to design gene circuits

    Hiscock, T. W.
    BMC Bioinformatics, vol. 20, 214
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • A single-cell molecular map of mouse gastrulation and early organogenesis

    Pijuan-Sala, B., Griffiths, J. A., Guibentif, C., Hiscock, T. W., Jawaid, W., Calero-Nieto, F. J., Mulas, C., Ibarra-Soria, X., Tyser, R. C., Ho, D. L. L., Reik, W., Srinivas, S., Simons, B. D., Nichols, J., Marioni, J. C., Göttgens, B.
    Nature, vol. 566, pp. 490-495
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]
    • [ONLINE]
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