51cg

People

Professor Alison Avenell

Professor Alison Avenell
Professor Alison Avenell
Professor Alison Avenell

Clinical Chair in Health Services Research

51cg
Email Address
a.avenell@abdn.ac.uk
Telephone Number
+44 (0)1224 438164
Office Address

Health Services Research Unit
3rd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Alison Avenell joined the Unit in 1998, as a Clinical Research Fellow. She was subsequently funded by the Chief Scientist Office (CSO) of the Scottish Government Health Directorates as a Clinical Research Fellow to undertake research in the MRC funded RECORD trial, which examined the effect of calcium and/or vitamin D supplementation in the secondary prevention of osteoporotic fractures. She also led the MAVIS trial which examined the effectiveness of vitamin and mineral supplementation in preventing infections in older people, and helped lead the SIGNET trial of glutamine and selenium supplementation in critical illness. She was a CSO funded Career Scientist and currently has a clinical chair in health services research and is an Honorary Consultant in Clinical Biochemistry, undertaking systematic reviews and randomised controlled trials of treatments for adult obesity, and under-nutrition in clinical practice.

Research

Current Research

Current projects

Completed projects

Publications

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  • EFFECT OF PERINDOPRIL ON PHYSICAL PERFORMANCE, MUSCLE MASS AND QUALITY OF LIFE IN OLDER PEOPLE WITH SARCOPENIA: RESULTS: FROM THE

    Witham, M. D., Adamson, S., Avenell, A., Band, M. M., Donnan, P. T., George, J., Hapca, A., Hume, C., Kemp, P., McKenzie, E., Pilvinyte, K., Smith, K., Struthers, A. D., Sumukadas, D., LACE Study Grp
    Age and Ageing, vol. 51, no. S1, 666
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • Timeliness and content of retraction notices for publications by a single research group

    Grey, A., Avenell, A., Bolland, M.
    Accountability in Research, vol. 29, no. 6, pp. 347-378
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Citation of retracted publications: A challenging problem

    Bolland, M. J., Grey, A., Avenell, A.
    Accountability in Research, vol. 29, no. 1, pp. 18-25
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • The effectiveness of weight-loss lifestyle interventions for improving fertility in women and men with overweight or obesity and infertility: A systematic review update of evidence from randomized controlled trials

    Hunter, E., Avenell, A., Maheshwari, A., Stadler, G., Best, D.
    Obesity Reviews, vol. 22, no. 12, e13325
    Contributions to Journals: Review articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Cost-effectiveness of bariatric surgery and non-surgical weight management programmes for adults with severe obesity: a decision analysis model

    Boyers, D., Retat, L., Jacobsen, E., Avenell, A., Aveyard, P., Corbould, E., Jaccard, A., Cooper, D., Robertson, C., Aceves-Martins, M., Xu, B., Skea, Z., de Bruin, M., REBALANCE team
    International Journal of Obesity, vol. 45, no. 10, pp. 2179-2190
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Associations between Frailty, Physical Performance, and Renal Biomarkers in Older People with Advanced Chronic Kidney Disease

    Smith, G., Avenell, A., Band, M. M., Hampson, G., Lamb, E. J., Littleford, R. C., McNamee, P., Soiza, R., Sumukadas, D., Witham, M. D.
    European Geriatric Medicine, vol. 12, pp. 943–952
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Vitamin D deficiency, supplementation and testing: have we got it right in New Zealand?

    Bolland, M. J., Avenell, A., Grey, A.
    The New Zealand medical journal, vol. 134, no. 1541, pp. 86-95
    Contributions to Journals: Articles
    • [ONLINE]
    • [ONLINE]

  • Identical summary statistics were uncommon in randomized trials and cohort studies

    Bolland, M. J., Gamble, G. D., Avenell, A., Grey, A.
    Journal of Clinical Epidemiology, vol. 136, pp. 180-188
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Correcting the scientific record– A broken system?

    Bolland, M. J., Grey, A., Avenell, A., Klein, A. a.
    Accountability in Research, vol. 28, no. 5, pp. 265-279
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Prevalence of biochemical osteomalacia in adults undergoing vitamin D testing

    Bolland, M. J., Avenell, A., Grey, A.
    Clinical Endocrinology, vol. 95, no. 1, pp. 74-83
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Recruitment strategies for sarcopenia trials: lessons from the LACE randomised controlled trial

    Witham, M. D., Achison, M., Aspray, T. J., Avenell, A., Band, M. M., Donnan, P. T., George, J., Hapca, A., Hume, C. L., Kemp, P., Pilvinyte, K., Sayer, A. A., Sayer, A. A., Smith, K. T., Struthers, A., Sumukadas, D.
    JCSM Rapid Communications, vol. 4, no. 2, pp. 93-102
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Protocol for a randomised controlled trial comparing laparoscopic cholecystectomy with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones (C-Gall trial)

    Ahmed, I., Innes, K., Brazzelli, M., Gillies, K., Newlands, R., Avenell, A., Hernández, R., Blazeby, J., Croal, B., Hudson, J., MacLennan, G., McCormack, K., McDonald, A., Murchie, P., Ramsay, C.
    BMJ Open, vol. 11, no. 3, e039781
    Contributions to Journals: Articles
    • [ONLINE]
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • WHAT ARE THE ASSOCIATIONS BETWEEN RENAL BIOCHEMISTRY AND PHYSICAL PERFORMANCE IN OLDER PATIENTS WITH ADVANCED CHRONIC KIDNEY DISEASE? FINDINGS FROM THE BICARB TRIAL COHORT

    Witham, M. D., Lamb, E. J., Sumukadas, D., Band, M. M., Soiza, R. L., Hampson, G., McNamee, P., Avenell, A.
    Age and Ageing, vol. 50, no. Supp 1, 47
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • Vitamin D supplementation and testing in the UK: Costly but ineffective?

    Bolland, M. J., Avenell, A., Smith, K., Witham, M. D., Grey, A.
    The BMJ, vol. 372, n484
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]
    • [ONLINE]

  • Participant withdrawals were unusually distributed in randomized trials with integrity concerns: a statistical investigation

    Bolland, M. J., Gamble, G. D., Avenell, A., Cooper, D., Grey, A.
    Journal of Clinical Epidemiology, vol. 131, pp. 22-29
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Population vitamin D supplementation in UK adults: too much of nothing?

    Avenell, A., Bolland, M. J., Grey, A.
    Drug and Therapeutics Bulletin (DTB), vol. 59, no. 1, pp. 7-12
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Empirically generated reference proportions for baseline p values from rounded summary statistics

    Bolland, M. J., Gamble, G. D., Grey, A., Avenell, A.
    Anaesthesia, vol. 75, no. 12, pp. 1685-1687
    Contributions to Journals: Letters
    • [ONLINE] DOI:
    • [ONLINE]

  • Text messaging and financial incentives to encourage weight loss in men with obesity: the Game of Stones feasibility RCT

    Dombrowski, S. U., Mcdonald, M., van der Pol, M., Grindle, M., Avenell, A., Carroll, P., Calveley, E., Elders, A., Glennie, N., Gray, C. M., Harris, F. M., Hapca, A., Jones, C., Kee, F., McKinley, M. C., Skinner, R., Tod, M., Hoddinott, P.
    Public Health Research, vol. 8, no. 11, pp. 1-258
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Assessing and Raising Concerns 51cg Duplicate Publication, Authorship Transgressions and Data Errors in a Body of Preclinical Research

    Grey, A., Avenell, A., Gamble, G., Bolland, M.
    Science and Engineering Ethics, vol. 26, pp. 2069-2096
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Incorrect and misleading claims regarding vitamin d

    Bolland, M. J., Avenell, A.
    Irish Medical Journal, vol. 113, no. 7, P145
    Contributions to Journals: Comments and Debates
    • [ONLINE]
    • [ONLINE]

  • Sodium bicarbonate to improve physical function in patients over 60 years with advanced chronic kidney disease: the BiCARB RCT

    Witham, M. D., Band, M., Chong, H. Y., Donnan, P. T., Hampson, G., Hu, M. K., Littleford, R. C., Lamb, E., Kalra, P., Kennedy, G., McNamee, P., Plews, D., Rauchhaus, P., Soiza, R. L., Sumukadas, D., Warwick, G., Avenell, A.
    Health Technology Assessment, vol. 24, no. 27, pp. 1-120
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • A systematic review of UK based long-term non-surgical interventions for people with severe obesity (BMI ≥35kg/m2)

    Aceves Martins, M., Robertson, C., Cooper, D., Avenell, A., Stewart, F., Aveyard, P., de Bruin, M., REBALANCE team
    Journal of Human Nutrition and Dietetics, vol. 33, no. 3, pp. 351-372
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Concerns 51cg the Integrity of the Yamaguchi Osteoporosis Prevention Study (YOPS) Report: Am J Med. 2004;117:549-555

    Avenell, A., Grey, A., Gamble, G. D., Bolland, M. J.
    American Journal of Medicine, vol. 133, no. 6, pp. e311-e314
    Contributions to Journals: Letters
    • [ONLINE] DOI:
    • [ONLINE]

  • Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis (BiCARB): a pragmatic randomised, double-blind, placebo-controlled trial

    Witham, M. D., McNamee, P., Soiza, R., Avenell, A., BiCARB Study Group
    BMC medicine , vol. 18, 91
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis: The BiCARB randomised controlled trial

    Witham, M. D., Band, M., Chong, H. Y., Donnan, P. T., Hampson, G., Hu, M. K., Littleford, R., Lamb, E., Kalra, P., Kennedy, G., McNamee, P., Plews, D., Rauchhaus, P., Soiza, R. L., Sumukadas, D., Warwick, G., Avenell, A.
    Health Technology Assessment, vol. 18, 91
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Challenges of Systematic Reviews of Economic Evaluations: A Review of Recent Reviews and an Obesity Case Study

    Jacobsen, E., Boyers, D., Avenell, A.
    Pharmacoeconomics, vol. 38, no. 3, pp. 259-267
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Game of Stones: feasibility randomised controlled trial of how to engage men with obesity in text message and incentive interventions for weight loss

    Dombrowski, S. U., McDonald, M., van der Pol, M., Grindle, M., Avenell, A., Carroll, P., Calveley, E., Elders, A., Glennie, N., Gray, C. M., Harris, F. M., Hapca, A., Jones, C., Kee, F., McKinley, M. C., Skinner, R., Tod, M., Hoddinott, P.
    BMJ Open, vol. 10, no. 2, 032653
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Check for publication integrity before misconduct

    Grey, A., Bolland, M. J., Avenell, A., Klein, A. A., Gunsalus, C. K.
    Nature, vol. 577, no. 7789, pp. 167-169
    Contributions to Journals: Comments and Debates
    • [ONLINE] DOI:
    • [ONLINE]

  • Evaluating ethics oversight during assessment of research integrity

    Grey, A., Bolland, M., Avenell, A.
    Research integrity and peer review, vol. 4, 22
    Contributions to Journals: Letters
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • An investigation into the impact and implications of published papers from retracted research: systematic search of affected literature

    Avenell, A., Stewart, F., Grey, A., Gamble, G., Bolland, M.
    BMJ Open, vol. 9, no. 10, 031909
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Can surgery be avoided in patients with symptomatic gallstone disease and no complications?

    Brazzelli, M., Avenell, A., Gillies, K., Ramsay, C., Ahmed, I.
    The BMJ, vol. 367, no. 8218, l5709
    Contributions to Journals: Comments and Debates
    • [ONLINE] DOI:
    • [ONLINE]

  • Baseline P  value distributions in randomized trials were uniform for continuous but not categorical variables

    Bolland, M. J., Gamble, G. D., Avenell, A., Grey, A., Lumley, T.
    Journal of Clinical Epidemiology, vol. 112, pp. 67-76
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Correcting Meta-analyses and Reviews Affected by Retracted Research

    Grey, A., Avenell, A., Bolland, M.
    JAMA Internal Medicine, vol. 179, no. 7, pp. 1005
    Contributions to Journals: Comments and Debates
    • [ONLINE] DOI:
    • [ONLINE]
    • [ONLINE]
    • [ONLINE]

  • Rounding, but not randomization method, non-normality, or correlation, affected baseline P-value distributions in randomized trials

    Bolland, M. J., Gamble, G. D., Avenell, A., Grey, A.
    Journal of Clinical Epidemiology, vol. 110, pp. 50-62
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]
    • [ONLINE]

  • Fractures in Adults After Weight Loss from Bariatric Surgery and Weight Management Programs for Obesity: Systematic Review and Meta-analysis

    Ablett, A. D., Boyle, B. R., Avenell, A.
    Obesity Surgery, vol. 29, no. 4, pp. 1327-1342
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • 25-Hydroxyvitamin D – Should labs be measuring it?

    Avenell, A., Bolland, M. J., Grey, A.
    Annals of Clinical Biochemistry, vol. 56, no. 2, pp. 188-189
    Contributions to Journals: Editorials
    • [ONLINE] DOI:
    • [ONLINE]

  • Quality of reports of investigations of research integrity by academic institutions

    Grey, A., Bolland, M., Gamble, G., Avenell, A.
    Research integrity and peer review, vol. 4, 3
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Vitamin D supplementation and musculoskeletal health - Authors' reply

    Bolland, M. J., Grey, A., Avenell, A.
    The lancet. Diabetes & endocrinology, vol. 7, no. 2, pp. 88-89
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • The acceptability and feasibility of weight management programmes for adults with severe obesity: A qualitative systematic review

    Skea, Z., Aceves Martins, M., Robertson, C., de Bruin, M., Avenell, A.
    BMJ Open, vol. 9, no. 9, e029473
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation

    Avenell, A., Robertson, C., Skea, Z., Jacobsen, E., Boyers, D., Cooper, D., Aceves-Martins, M., Retat, L., Fraser, C., Aveyard, P., Stewart, F., MacLennan, G., Webber, L., Corbould, E., Xu, B., Jaccard, A., Boyle, B., Duncan, E., Shimonovich, M., de Bruin, M.
    Health Technology Assessment, vol. 22, no. 68, pp. 1-286
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Enough data to draw conclusions about vitamin D and bone health

    Bolland, M. J., Avenell, A., Grey, A.
    BMJ, vol. 363, k4755
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Effects of vitamin D supplementation on musculoskeletal health: a systematic review, meta-analysis, and trial sequential analysis

    Bolland, M. J., Grey, A., Avenell, A.
    The lancet. Diabetes & endocrinology, vol. 6, no. 11, pp. 847-858
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Assessment of research waste part 1: an exemplar from examining study design, surrogate and clinical endpoints in studies of calcium intake and vitamin D supplementation

    Bolland, M. J., Avenell, A., Grey, A.
    BMC Medical Research Methodology, vol. 18, no. 1, 103
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Assessment of research waste part 2: wrong study populations- an exemplar of baseline vitamin D status of participants in trials of vitamin D supplementation

    Bolland, M. J., Grey, A., Avenell, A.
    BMC Medical Research Methodology, vol. 18, no. 1, 101
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Inaccurate retraction notice for meta-analysis by Iwamoto et al

    Grey, A., Avenell, A., Gamble, G., Bolland, M.
    Acta Neurologica Scandinavica, vol. 138, no. 3, pp. 263
    Contributions to Journals: Letters
    • [ONLINE] DOI:
    • [ONLINE]

  • Revised Meta-analysis of Vitamin K and Fractures

    Grey, A., Avenell, A., Bolland, M.
    JAMA Internal Medicine, vol. 178, no. 8, pp. 1135
    Contributions to Journals: Comments and Debates
    • [ONLINE] DOI:

  • A mixed-methods evaluation of a community pharmacy signposting service to a commercial weight-loss provider

    Inch, J., Avenell, A., Aucott, L., Watson, M. C.
    Public Health Nutrition, vol. 21, no. 12, pp. 2311-2319
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • A randomised investigation of journal responses to academic and journalist enquiry about possible scientific misconduct

    Bolland, M. J., Avenell, A., Gamble, G. D., Buranyi, S., Grey, A.
    BMC Research Notes, vol. 11, 521
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Cancer and vitamin D supplementation: a systematic review and meta-analysis

    Goulao, B., Stewart, F., Ford, J. A., MacLennan, G., Avenell, A.
    The American Journal of Clinical Nutrition, vol. 107, no. 4, pp. 652-663
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Concerns 51cg the Integrity of Sato et al. Am J Med. 2005;118:1250-1255

    Grey, A., Avenell, A., Gamble, G., Bolland, M.
    American Journal of Medicine, vol. 131, no. 3, pp. e107-e108
    Contributions to Journals: Letters
    • [ONLINE] DOI:
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