51cg

People

Dr Raja Edwin-Amalraj

Dr Raja Edwin-Amalraj
Dr Raja Edwin-Amalraj
Dr Raja Edwin-Amalraj

M.Sc., Ph.D., AFHEA.,

Advanced Research Fellow

51cg
Email Address
amalraj.raja@abdn.ac.uk
Telephone Number
+44 (0)1224 437147
Office Address

Telephone :01224-437147 Fax :01224 437857 Medical Statistics Team Division of Applied Health Sciences 51cg Polwarth Building Foresterhill ABERDEEN AB25 2ZD UK

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Edwin Amalraj Raja joined Public Health as a Research Fellow in Medical Statistics in May 2006. In 1983, Edwin Amalraj Raja got his undergraduate degree in Statistics from St.Joseph's College, Trichy, India and postgraduate degree in Statistics from Loyola College, Chennai, India.

Edwin Amalraj Raja completed advanced training on the application of Statistics in the Department of Biostatistics, Christian Medical College, Vellore. He worked in 'Advanced Center for Clinical Epidemiological Research and Training Centre' at Madras Medical College, Chennai.  His work with the Tamil Nadu Government funded project on 'Epidemiology of Head Injury'   led him to pursue and obtain his PhD in 'Biostatistical Application in the Prediction of Outcome of Severe Head Injury' from the Tamil Nadu M G R Medical University, Chennai, India.

Within Institute of Apllied Health Sciences (IAHS), Edwin Amalraj Raja is involved in the analysis of research projects, especially statistical modelling of longitudinal data, Statistical methods in Epidemiology, etc., He is also involved in teaching and training in Medical statistics organised by the Medical Statistics Team for staff and students of this University.

 

Memberships and Affiliations

Internal Memberships

Member of School Ethics Committee

Member of Health and Safety, School of Medicine

External Memberships

Statistical expert for North of Scotland Research Ethics Committee (NRES)

Research

Research Overview

Clinical Areas of Consulting Experience

Obstetric & Gynaecology  Factors associated with Maternal complications, Maternal BMI & Offspring CVD , Mortality

Infertility                      Classification of infertility and demographic factors affecting fertility

Maternal Obesity           Offspring developing CVD           

Renal disease                The relationship between renal function parameters and blood pressure

common Cancers           Factors contributing to time to consult GP, provider delay & stage , Mortality

Diabetes Mellitus            Prevalence, risk factors, incidence of complications,  patients perception of their complication

                                

Current Research

Methodological research interests

Prediction Modelling

Categorical data analysis

Statistical methods in Epidemiology

Analysis of repeated measures / Longitudinal Data Analysis / Multilevel Modeling

Structural Equation Modelling

Cubic spline analysis - Non-linear relationship between continuous variable and outcome

Survival analysis- Competing risks- recurrent events

Supervision

Looking for a PhD student

Title: The impact of duration of freezing of IVF embryos on pregnancy and perinatal outcomes – analysis of UK national data

Background of the research proposal: 

IVF (in-vitro fertilisation) is the recommended treatment for couples with unresolved infertility. It involves mixing eggs and sperm to create embryos which are then cultured in the laboratory. Usually, the best embryo is then put back in the womb, while others can be frozen for future use. The use of frozen embryos has become popular across the globe in recent years, accounting for 41% of all IVF treatments in 2019 in UK. Although many embryos are frozen for short durations, others can be kept in the freezer for many months or years and it is believed that patients can use them at any time without affecting their chances of pregnancy rates or the health of their babies.

Aim: To find an association between the duration of embryo freezing and pregnancy and perinatal outcomes among couples treated for infertility

Dataset: This study will use information of treatments undertaken between 2000 and 2019 from the Human Fertilisation Embryology Authority (HFEA) database which holds data of all IVF treatments undertaken in the UK licensed clinics, to explore the impact of the duration of embryo freezing on IVF live birth rate and safety of children.

Exposure:  the duration of embryo freezing 

Outcomes: The main outcome measures are live birth, gestational age (preterm vs term), birthweight (small/large for gestational age vs normal for gestational age) and congenital anomalies. The results of the proposed research will provide patients and clinicians with the necessary information so that they can make informed choices in the future.

Statistical Analyses: The student is expected to come up with appropriate statistical methods and use machine learning techniques to address the research question or objective of the study.

Funding and Grants

Murchie P, Lisa I, Raja EA, Lee AJ. Do melanoma excised in primary care have different outcomes to those excised in secondary care? Friends of ANCHOR £10,000

David M, Bhattacharya S, Abha M, Raja EA. Perinatal outcomes of singletons born following in-vitro fertilisation: a comparison of different embryo transfer strategies using UK data. NHS Grampian Endowment .(submitted)

Mairead B, Sohinee B, Andrea W, Gail F, EA Raja and Ipek. Maternal Body Mass Index in pregnancy ana cardiometabolic risk in monozygotic and dizygotic twin offspring (submitted to Wellbeing of Women)

Sohinee B, Geraldine M, Rebecca R and EA Raja. Reproductive consequences of third and fourth degree perineal tears (submitted to CHSS)

Teaching

Teaching Responsibilities

Teaching in the Short courses organised by Medical Statistics Team

Introduction to Medical Statistics

Intermediate Statistics Course

B medical Science SPSS practicals II

M Sc Public Health practicals

Publications

Page 1 of 3 Results 1 to 25 of 67

  • The influence of rural residency on the uptake of screening for breast, cervical and colorectal cancers in Scotland

    Iversen, L., Raja, E. A., Nath, M., Lip, G., Speirs, V., Collins, J., Philip, L., Hanley, S. J., Murchie, P.
    Journal of Public Health, vol. 48, no. 2, pp. 467–476
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Cesarean section at full dilatation in the first birth is not associated with an increased risk of subsequent miscarriage: a historical cohort study

    Woolner, A., Raja, E. A., Black, M.
    Acta Obstetricia et Gynecologica Scandinavica, vol. 103, no. 10, pp. 2092-2100
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Interrupted time series analysis of admissions before and after introduction of rapid review clinics in two centres

    Chik, C. W., Christy, C. L. H., Raja, A., Turner, S. W.
    Archives of Disease in Childhood, vol. 109, no. 10, pp. 869-870
    Contributions to Journals: Letters
    • [ONLINE] DOI:
    • [ONLINE]

  • Paternal migration and child stunting in India: An analysis of NFHS-5 data.

    Guntupalli, A., Gaur, K., Raja, E. A., Keshri, K.
    Economic and Political Weekly, vol. 59, no. 35
    Contributions to Journals: Articles
    • [ONLINE]
    • [OPEN ACCESS]

  • Is arrival by ambulance a risk factor for myocardial infarction in emergency department patients with cardiac sounding chest pain?

    Murray, J., Raja, E. A., Plascevic, J., Jacunski, M., Cooper, J. G.
    Emergency Medicine Journal, vol. 41, no. 6, pp. 376-378
    Contributions to Journals: Letters
    • [ONLINE] DOI:
    • [ONLINE]

  • Symptom duration, ambulance response and emergency department transfer time in relation to development of myocardial infarction in patients with chest pain

    Milne, H., Raja, E. A., Cooper, J.
    Contributions to Conferences: Papers

  • Risk of spontaneous preterm birth elevated after first cesarean delivery at full dilatation: a retrospective cohort study of over 30,000 women

    Woolner, A., Raja, E. A., Bhattacharya, S., Black, M.
    American Journal of Obstetrics and Gynecology, vol. 230, no. 3, pp. 358.e1-358.e13
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Perinatal outcomes in singleton live births after blastocyst transfer: an analysis of 60,926 in vitro fertilization cycles from the United Kingdom

    Marconi, N., Raja, E. A., Bhattacharya, S., Maheshwari, A.
    Fertility and Sterility, vol. 120, no. 2, pp. 312-320
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Maternal and perinatal outcomes of prolonged second stage of labour: a historical cohort study of over 51,000 women

    Young, C., Bhattacharya, S., Woolner, A., Ingram, A., Smith, N., Raja, E., Black, M.
    BMC Pregnancy and Childbirth, vol. 23, no. 1, 467
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • A comparison of perinatal outcomes following fresh blastocyst or cleavage stage embryo transfer in singletons and twins and between singleton siblings

    Raja, E., Bhattacharya, S., Maheshwari, A., McLernon, D. J.
    Human Reproduction Open, vol. 2023, no. 2, hoad003
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • In patients with chest pain suspicious for ACS, is arrival by ambulance associated with increased likelihood of myocardial infarction?

    Murray, J., Raja, E. A., Cooper, J.
    Royal College of Emergency Medicine Annual Scientific Conference, pp. 970
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • Comparison of perinatal outcomes following frozen or fresh embryo transfer: separate analyses of singleton, twin and sibling live births from a linked national In vitro fertilisation registry

    Raja, E. A., Bhattacharya, S., Maheshwari, A., McLernon, D.
    Fertility and Sterility, vol. 118, no. 2, pp. 323-334
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Reducing asthma attacks in children using exhaled nitric oxide (RAACENO) as a biomarker to inform treatment strategy: a multicentre, parallel, randomised, controlled, phase 3 trial

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongste, J. C., Pijnenburg, M. W., Thomas, M., Price, D.
    The Lancet. Respiratory medicine, vol. 10, no. 6, pp. 584-592
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Treatment guided by fractional exhaled nitric oxide in addition to standard care in 6- to 15-year-olds with asthma: the RAACENO RCT

    Turner, S., Cotton, S., Wood, J., Bell, V., Raja, E. A., Scott, N., Morgan, H., Lawrie, L., Emele, D., Kennedy, C., Scotland, G., Fielding, S., MacLennan, G., Norrie, J., Forrest, M., Gaillard, E. A., de Jongeste, J., Pijnenburg, M. W., Thomas, M., Price, D.
    Efficacy and Mechanism Evaluation, vol. 9, no. 4
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: Cohort study of 151,141 singleton pregnancies

    Zafeiri, A., Raja, E. A., Mitchell, R. T., Hay, D. C., Bhattacharya, S., Fowler, P.
    BMJ Open, vol. 12, no. 5, e048092
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Predicting personalized cumulative live birth following in vitro fertilization

    McLernon, D. J., Raja, E., Toner, J. P., Baker, V. L., Doody, K. J., Seifer, D. B., Sparks, A. E., Wantman, E., Lin, P. C., Bhattacharya, S., Van Voorhis, B. J.
    Fertility and Sterility, vol. 117, no. 2, pp. 326-338
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Maternal over-the-counter analgesics use during pregnancy and adverse perinatal outcomes: cohort study of 151,141 singleton pregnancies

    Zafeiri, A., Raja, E. A., Hay, D. C., Mitchell, R. T., Bhattacharya, S., Fowler, P. A.
    Human Reproduction, vol. 36, no. S1, pp. 469-469
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • The association between opening a short stay paediatric assessment unit and trends in short stay hospital admissions

    Turner, S., Raja, E.
    BMC Health Services Research, vol. 21, no. 1, pp. 523
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Does admission prevalence change after reconfiguration of inpatient services? An interrupted time series analysis of the impact of reconfiguration in five centres

    Martin, J., Raja, E. A., Turner, S.
    BMC Health Services Research, vol. 21, no. 1, 75
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Family history and risk of miscarriage: a systematic review and meta-analysis of observational studies

    Woolner, A. M., Nagdeve, P., Raja, E. A., Bhattacharya, S., Bhattacharya, S.
    Acta Obstetricia et Gynecologica Scandinavica, vol. 99, no. 12, pp. 1584-1594
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Corrigendum. Testing the twin testosterone transfer hypothesis: intergenerational analysis of 317 dizygotic twins born in Aberdeen, Scotland

    Talia, C., Raja, E., Bhattacharya, S., Fowler, P. A.
    Human reproduction (Oxford, England), vol. 35, no. 10, pp. 2401-2402
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Testing the twin testosterone transfer hypothesis: Intergenerational analysis of 317 dizygotic twins born in Aberdeen, Scotland

    Talia, C., Raja, E., Bhattacharya, S., Fowler, P. A.
    Human Reproduction, vol. 35, no. 7, pp. 1702-1710
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Changing risk factors for placental abruption: a case crossover study using routinely collected data from Finland, Malta and Aberdeen

    Anderson, E., Raja, E. A., Shetty, A., Gissler, M., Gatt, M., Bhattacharya, S., Bhattacharya, S.
    PloS ONE, vol. 15, no. 6, e0233641
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Testing the Twin Testosterone Transfer Hypothesis: Intergenerational Analysis of 317 Twins Born in Aberdeen, Scotland

    Talia, C., Raja, E., Bhattacharya, S., Fowler, P. A.
    67th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI), pp. 288A
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:
    • [ONLINE]

  • Inherited susceptibility to miscarriage: a nested case-control study of 31565 women from an intergenerational cohort

    Woolner, A. M. F., Raja, E., Bhattacharya, S., Danielian, P., Bhattacharya, S.
    American Journal of Obstetrics and Gynecology, vol. 222, no. 2, pp. 168.e1-168.e8
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]
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