51cg

People

Professor Claude Wischik

Professor Claude Wischik
Professor Claude Wischik
Professor Claude Wischik

Chair in Mental Health (Clin)

51cg
Email Address
c.m.wischik@abdn.ac.uk
Office Address

TauRx Therapeutics Ltd

1st Floor, Sir Moir Lockhead Building

395 King Street

Aberdeen

AB24 5RP

United Kingdom

School/Department
School of Medicine, Medical Sciences and Nutrition
Research

Research Overview

Molecular Neuropathology of Alzheimer's Disease, and in particular the therapeutic intervention of tau pathology

Publications

Page 3 of 12 Results 21 to 30 of 115

  • Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model

    Zadrozny, M., Drapich, P., Gasiorowska-Bien, A., Niewiadomski, W., Harrington, C. R., Wischik, C. M., Riedel, G., Niewiadomska, G.
    Cells, vol. 13, no. 7, 642
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Assays for the Screening and Characterization of Tau Aggregation Inhibitors

    Horsley, D., Rickard, J. E., Vorley, T., Leeper, M. F., Wischik, C. M., Harrington, C. R.
    Tau Protein: Methods and Protocols. 2 edition, pp. 93-104, 12 pages
    Chapters in Books, Reports and Conference Proceedings: Chapters (Peer-Reviewed)
    • [ONLINE] DOI:

  • Solubility of α-synuclein species in the L62 mouse model of synucleinopathy

    Schwab, K., Magbagbeolu, M., Theuring, F., Harrington, C., Wischik, C., Riedel, G.
    Scientific Reports, vol. 14, 6239
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Apathy-like behaviour in tau mouse models of Alzheimer’s disease and frontotemporal dementia

    Robinson, L., Dreesen, E., Mondesir, M., Harrington, C., Wischik, C., Riedel, G.
    Behavioural Brain Research, vol. 456, 114707
    Contributions to Journals: Articles
    • [ONLINE]
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • A Meta-Analysis on Presynaptic Changes in Alzheimer's Disease

    Anschuetz, A., Schwab, K., Harrington, C. R., Wischik, C. M., Riedel, G.
    Journal of Alzheimer's Disease, vol. 97, no. 1, pp. 145-162
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Significant dose-dependent reduction in neurofilament light chain concentration in plasma with oral tau aggregation inhibitor hydromethylthionine mesylate

    Wischik, C. M., Schelter, B., Penny, L. K., Miller, S., Stefanacci, R., Heslegrave, A., Zetterberg, H.
    Alzheimer's Dementia, vol. 19, no. S24, e083153
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Exploring the Anti-Hypoxaemia Effect of Hydromethylthionine: A Prospective Study of Phase 3 Clinical Trial Participants

    Arastoo, M., Mazanetz, M. P., Miller, S., Shiells, H., Hull, C., Robinson, K., Storey, J. M., Harrington, C. R., Wischik, C. M.
    International Journal of Molecular Sciences, vol. 24, no. 18, 13747
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice

    Kondak, C., Leith, M., Baddeley, T. C., Santos, R. X., Harrington, C. R., Wischik, C. M., Riedel, G., Klein, J.
    International Journal of Molecular Sciences, vol. 24, no. 13, 10810
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Utility of Blood-Based Tau Biomarkers for Mild Cognitive Impairment and Alzheimer’s Disease: Systematic Review and Meta-Analysis

    Zabala-Findlay, A., Penny, L. K., Lofthouse, R. A., Porter, A. J., Palliyil, S., Harrington, C. R., Wischik, C. M., Arastoo, M.
    Cells, vol. 12, no. 8, 1184
    Contributions to Journals: Review articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • An Additive-Free Model for Tau Self-Assembly

    Al-Hilaly, Y. K., Marshall, K. E., Lutter, L., Biasetti, L., Mengham, K., Harrington, C. R., Xue, W. F., Wischik, C. M., Serpell, L. C.
    Methods in molecular biology (Clifton, N.J.), vol. 2551, pp. 163-188
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]
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