MRCP, MSc, MD
Reader (Clinical)
- 51cg
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- Email Address
- carl.counsell@abdn.ac.uk
- Office Address
Room 1:009, Polwarth Building Division of Applied Health Sciences 51cg Foresterhill Aberdeen AB25 2ZD
- School/Department
- School of Medicine, Medical Sciences and Nutrition
Biography
Carl is a clinical reader and honorary consultant in neurology. He graduated in medicine from Cambridge University in 1988, did his early postgraduate medical training in London, Newcastle and Falkirk and then trained in neurology, stroke and epidemiology in Edinburgh. He spent a year in Melbourne where he specialised in movement disorders before taking up his present post in 2001. A committed Christian, he would like to have more time to serve in his church and develop his interests in Fairtrade and conservation.
Latest Publications
Personalised prediction of institutionalisation in Parkinson’s: prognostic factor identification and model development and validation using IPD meta-analysis
Parkinsonism and Related Disorders, vol. 149, 108390Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
- [ONLINE]
Prognosis in Parkinson’s disease: an individual-patient-data meta-analysis of six European incidence cohorts
Movement Disorders, vol. 41, no. 7, pp. 1798-1811Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Multi-locus genetic dosage shapes cognitive disease progression in Parkinson’s patients: 15-year meta-analysis of 24 cohorts
npj Parkinson's DiseaseContributions to Journals: Articles- [ONLINE] DOI:
Digitally enabled therapy for chronic tic disorders and Tourette Syndrome: a systematic review and economic evaluation
Health Technology Assessment, vol. 30, no. 8Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Systematic review of prognostic models in Parkinson’s disease
npj Parkinson's Disease, vol. 11, 266Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
- Research
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Research Overview
Carl is a consultant neurologist with subspecialty interest in movement disorders. His main research interests are in evidence-based medicine and broader aspects of clinical epidemiology such as incidence and prognostic studies, particularly in relation to Parkinson's disease, other movement disorders and stroke. His team have established several cohorts of parkinsonian patients for long-term follow-up and supported a number of non-industry sponsored clinical trials and Cochrane reviews, whilst also trying to promote multidisciplinary neurology research in Aberdeen.
Research Specialisms
- Clinical Medicine
Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is , published under the licence.
Current Research
The PINE study: a population-based incidence cohort of people with Parkinson's disease and other parkinsonian disorders, along with their carers and controls who are being followed up lifelong to establish long-term prognosis.
The Parkinson's Incidence Cohorts Collaboration: an individual patient data meta-analysis of all population- based incidence cohorts of Parkinson's disease to assess prognosis and allow prognostic modelling.
The Scottish PSP/CBD prevalence cohort: a cohort of people with two related Parkinson's plus disorders, Progressive Supranuclear Palsy and Corticobasal Degeneration as well as Parkinson's disease controls, to assess diagnostic and care pathways and prognosis.
Past Research
Cochrane systematic reviews of randomised trials in stroke care and Parkinson's disease
Prognostic modelling in acute stroke
Incidence of Parkinson's disease and other parkinsonian disorders in North-East Scotland
Prevalence of multiple sclerosis in North-East Scotland and northern isles
Randomised trial of physiotherapy for cervical dystonia
Knowledge Exchange
Member of Parkinson's Excellence Network
Collaborations
Cochrane Collaboration Stroke Review Group, Professors Charles Warlow and Peter Sandercock, University of Edinburgh, UK, 1993-98.
Scottish Audit of Intracranial Vascular Malformations, Professor Rustam Al-Shahi Salman, University of Edinburgh, UK, 2002-2014.
PDMED trial, Professor Carl Clarke, University of Birmingham, UK, 2004-2020.
Clinical trial methods in neurodegenerative diseases, Professor John Zajicek, University of Plymouth, UK, 2009-2014.
PDCOMM trial, Professor Sackley, University of Nottingham, UK, 2016-2023.
NICE technology appraisals for multiple sclerosis, Universities of Warwick and Exeter, UK, 2016-2022
Parkinson's Incidence Cohorts Collaboration, Professor Tysnes, Dr Guido Alves, Professor Lars Forsgren, Dr Caroline Williams-Gray, Dr Alison Yarnall, Universities of Stavanger (Norway), Umea (Sweden), Cambridge (UK) and Newcastle (UK), 2018 ongoing
PD Connect exercise trial, Julie Jones, Robert Gordon University, Aberdeen, UK, 2019-2022
Supervision
Dr Kate Taylor (MD), 2002-06, Incidence and prognosis of parkinsonism in north-east Scotland: a pilot study.
Clare Harris (MSc), 2006-08, PINE participants attitudes to brain donation.
Dr Robert Caslake (PhD), 2006-11, Incidence and short-term prognosis of Parkinson's disease and other parkinsonian disorders in north-east Scotland.
Dr Elizabeth Visser (MD), 2009-13, Prevalence of multiple sclerosis in northern Scotland.
Dr David McGhee (PhD), 2009-13, Improving clinical trial design in neurodegenerative diseases.
Dr Angus Macleod (PhD), 2012-15, Predicting mortality and dependency in Parkinson's disease.
Dr Diane Swallow (PhD), 2016-21, Assessing diagnostic pathways in progressive supranuclear palsy and corticobasal degeneration.
Funding and Grants
Research funding has been obtained from:
Parkinson’s UK, Scottish Chief Scientist Office, BMA Doris Hillier award, RS Macdonald Trust, BUPA Foundation, NHS Grampian endowments, Dystonia Society, National Institute for Health Research.
- Teaching
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Teaching Responsibilities
Lectures and clinical teaching of neurology for medical and dental students.
Supervising medical student elective and MSc projects
Non-course Teaching Responsibilities
Regent to medical students
- Publications
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Timed tests of motor function in Parkinson's disease
Parkinsonism & Related Disorders, vol. 16, no. 7, pp. 442-446Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial
The Lancet neurology, vol. 9, no. 6, pp. 581-591Contributions to Journals: Articles- [ONLINE] DOI:
Derivation of stem cells from human embryos: the principled arguments of potential donors and recipients
New Genetics and Society, vol. 29, no. 2, pp. 209-220Contributions to Journals: Articles- [ONLINE] DOI:
Documentation of cerebrospinal fluid opening pressure and other important aspects of lumbar puncture in acute headache
International Journal of Clinical Practice, vol. 64, no. 7, pp. 930-935Contributions to Journals: Articles- [ONLINE] DOI:
Medication management in people with Parkinson's disease during surgical admissions
Postgraduate Medical Journal, vol. 86, no. 1016, pp. 334-337Contributions to Journals: Articles- [ONLINE] DOI:
Predicting functional outcome after stroke by modelling baseline clinical and CT variables
Age and Ageing, vol. 39, no. 3, pp. 360-366Contributions to Journals: Articles- [ONLINE] DOI:
Diagnosis and pharmacological management of Parkinson's disease: summary of SIGN guidelines
British Medical Journal, vol. 340, pp. b5614Contributions to Journals: Articles- [ONLINE] DOI:
Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease
Cochrane Database of Systematic Reviews, no. 4, CD006661Contributions to Journals: Literature Reviews- [ONLINE] DOI:
Anticoagulants for Acute Ischemic Stroke
Stroke, vol. 40, no. 7, pp. 483-484Contributions to Journals: Articles- [ONLINE] DOI:
Economic burden of intracranial vascular malformations in adults: prospective population-based study
Stroke, vol. 40, no. 6, pp. 1973-1979Contributions to Journals: Articles- [ONLINE] DOI:
The presentation and clinical course of intracranial developmental venous anomalies in adults
Stroke, vol. 40, no. 6, pp. 1980-1985Contributions to Journals: Articles- [ONLINE] DOI:
'Not taken in by media hype': how potential donors, recipients and members of the general public perceive stem cell research
Human Reproduction, vol. 24, no. 5, pp. 1106-1113Contributions to Journals: Articles- [ONLINE] DOI:
Acute workload in a neurology department: Has it changed over the past 4 years?
Autumn Scientific Meeting of the Association of British Neurologists, pp. 456-457Contributions to Journals: Abstracts- [ONLINE] DOI:
Perioperative management of patients with Parkinson's disease
Autumn Scientific Meeting of the Association of British Neurologists, pp. 462Contributions to Journals: Abstracts- [ONLINE] DOI:
The presentation and clinical course of intracranial venous malformations in adults
Autumn Scientific Meeting of the Association of British Neurologists, pp. 454Contributions to Journals: Abstracts- [ONLINE] DOI:
Shape analysis of 123I-N-ω-fluoropropyl-2-β-carbomethoxy-3β-(4-iodophenyl) nortropane single-photon emission computed tomography images in the assessment of patients with parkinsonian syndromes
Nuclear Medicine Communications, vol. 30, no. 3, pp. 194-201Contributions to Journals: Articles- [ONLINE] DOI:
Parkinson's disease misdiagnosed as stroke
BMJ Case Reports, vol. 2009Contributions to Journals: Articles- [ONLINE] DOI:
Outcome after spontaneous and arteriovenous malformation-related intracerebral haemorrhage: Population-based studies
Brain, vol. 132, no. 2, pp. 537-543Contributions to Journals: Articles- [ONLINE] DOI:
- [ONLINE]
Changes in quality of life in people with Parkinson's disease left untreated at diagnosis
Age and Ageing, vol. 38, no. Suppl. 1, pp. i70Contributions to Journals: Abstracts- [ONLINE]
Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: The NNIPPS Study
Brain, vol. 132, no. 1, pp. 156-171Contributions to Journals: Articles- [ONLINE] DOI:
General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial
The Lancet, vol. 372, no. 9656, pp. 2132-2142Contributions to Journals: Articles- [ONLINE] DOI:
Patterns of brain arteriovenous malformation treatment
Stroke, vol. 39, no. 12, pp. 3216-3221Contributions to Journals: Articles- [ONLINE] DOI:
Changes in diagnosis with follow-up in an incident cohort of patients with parkinsonism
Journal of Neurology, Neurosurgery & Psychiatry, vol. 79, no. 11, pp. 1202-1207Contributions to Journals: Articles- [ONLINE] DOI:
Changes in diagnosis with follow-up in an incident cohort of patients with parkinsonism
Journal of Neurology, Neurosurgery & Psychiatry, vol. 79, no. 11Contributions to Journals: Articles- [ONLINE] DOI:
Recruitment bias resulted in poorer overall health status in a community-based control group
Journal of Clinical Epidemiology, vol. 61, no. 9, pp. 890-895Contributions to Journals: Articles- [ONLINE] DOI:
Anticoagulants for acute ischemic stroke
Chest, vol. 134, no. 2, pp. 466-467Contributions to Journals: Letters- [ONLINE] DOI:
Changes in quality of life in people with Parkinson's disease left untreated at diagnosis
Journal of Neurology, Neurosurgery & Psychiatry, vol. 79, no. 6, pp. 716-718Contributions to Journals: Articles- [ONLINE] DOI:
- [OPEN ACCESS]
The incidence and long-term prognosis of parkinsonian disorders in North East Scotland (the PINE Study): methods and initial recruitment
Movement Disorders, vol. 23 , no. Supp. 1, pp. S241Contributions to Journals: Articles- [ONLINE] DOI:
Developing a sensitive search strategy in MEDLINE to retrieve studies on assessment of the diagnostic performance of Imaging techniques
Radiology, vol. 247, no. 2, pp. 365-373Contributions to Journals: Articles- [ONLINE] DOI:
Outcome after interventional or conservative management of unruptured brain arteriovenous malformations: a prospective, population-based cohort study
The Lancet neurology, vol. 7, no. 3, pp. 223-230Contributions to Journals: Articles- [ONLINE] DOI:
Differences between intracranial vascular malformation types in the characteristics of their presenting haemorrhages: prospective, population-based study
Journal of Neurology, Neurosurgery & Psychiatry, vol. 79, no. 1, pp. 47-51Contributions to Journals: Articles- [ONLINE] DOI:
Anticoagulants for acute ischaemic stroke
Cochrane Database of Systematic Reviews, no. 4, CD000024Contributions to Journals: Articles- [ONLINE] DOI:
Antiplatelet therapy for acute ischaemic stroke
Cochrane Database of Systematic Reviews, no. 3, CD000029Contributions to Journals: Articles- [ONLINE] DOI:
Changes in diagnosis with follow-up in an incident cohort of patients with parkinsonism
Movement Disorders, vol. 23, no. Supplement 1, pp. S321-S321Contributions to Journals: Articles- [ONLINE] DOI:
Changes in quality of life in people with Parkinson's disease left untreated at diagnosis
Journal of Neurology, Neurosurgery & Psychiatry, vol. 79, no. 3, pp. 356-356Contributions to Journals: ArticlesLow-molecular-weight heparins or heparinoids versus standard unfractionated heparin for acute ischaemic stroke
Cochrane Database of Systematic Reviews, no. 3, CD000119Contributions to Journals: Articles- [ONLINE] DOI:
Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease: a systematic review of the literature
Movement Disorders, vol. 23 , no. Suppl. 1, pp. S200Contributions to Journals: Abstracts- [ONLINE] DOI:
The incidence and long-term outcome of parkinsonian disorders in North East Scotland (the PINE study): Methods and initial recruitment
Movement Disorders, vol. 23, no. Supplement 1, pp. S241Contributions to Journals: Articles- [ONLINE] DOI:
External validation of a six simple variable model of stroke outcome and verification in hyper-acute stroke
Journal of Neurology, Neurosurgery & Psychiatry, vol. 78, no. 12, pp. 1390-1391Contributions to Journals: Articles- [ONLINE] DOI:
Anti-Hu syndrome: A rare presentation and a very difficult decision
Practical Neurology, vol. 7, no. 5, pp. 336-341Contributions to Journals: Articles- [ONLINE] DOI:
Environmental risk factors for Parkinson's disease and parkinsonism: the Geoparkinson study
Occupational and Environmental Medicine, vol. 64, no. 10, pp. 666-672Contributions to Journals: Articles- [ONLINE] DOI:
Heterogeneity in male to female risk for Parkinson's disease
Journal of Neurology, Neurosurgery & Psychiatry, vol. 78, no. 8, pp. 905-906Contributions to Journals: Letters- [ONLINE] DOI:
Monoamine oxidase B inhibitors versus other dopaminergic agents in early Parkinson's disease (Review)
Cochrane Database of Systematic Reviews, no. 3, pp. 1-29Contributions to Journals: Review articles- [ONLINE] DOI:
- [ONLINE]
Non-completion of changes to prescribed medications in people with Parkinson's disease
Age and Ageing, vol. 36, no. 3, pp. 333-336Contributions to Journals: Letters- [ONLINE] DOI:
Systematic review of the prevalence of depression in Parkinson's disease
Spring Meeting of the Association of British Neurologists, pp. 1398-1398Contributions to Journals: Abstracts- [ONLINE]
The use and influence of FP-CIT SPECT in current practice: UK experience of 190 patients with uncertain parkinsonism
Spring Meeting of the Association of British Neurologists, pp. 1398-1398Contributions to Journals: Abstracts- [ONLINE]
Is it Parkinson's disease, and if not, what is it?
Practical Neurology, vol. 6, no. 3, pp. 154-165Contributions to Journals: ArticlesPilot study of the incidence and prognosis of degenerative parkinsonian disorders in Aberdeen, United Kingdom: methods and preliminary results
Movement Disorders, vol. 21, no. 7, pp. 976-982Contributions to Journals: Articles- [ONLINE] DOI:
Screening for undiagnosed parkinsonism in people aged 65 years and over in the community
Parkinsonism & Related Disorders, vol. 12, no. 2, pp. 79-85Contributions to Journals: Articles- [ONLINE] DOI:
Screening for undiagnosed parkinsonism in a random community sample of people aged 65 years and over
Clinical Neurosciences 2005 Meeting, pp. 140-141Contributions to Journals: Abstracts