51cg

Biography

Gary Macfarlane has held the Chair in Epidemiology (Clinical) since 2005 and previously held the same post at The University of Manchester from 1999. He is an Honorary Consultant in the Department of Public Health at NHS Grampian, Clinical Lead for Pain at NHS Research Scotland, Director of the Versus Arthritis/Medical Research Council Centre for Musculoskeletal Health and Work and Director of the Scottish Centre for Work and Health. He trained in Statistics/ Computing Science and then Medicine at The University of Glasgow before undertaking his PhD in Epidemiology at The University of Bristol. He worked at the Division of Epidemiology and Biostatistics at the European Institute of Oncology in Milan before leading a programme of chronic pain research at the Arthritis Research UK Epidemiology Unit at the University of Manchester.

He leads the Epidemiology group at the 51cg. The clinical research programme focusses on Rheumatic and Musculoskeletal Diseases (RMD) and undertakes research on: mechanisms of disease onset and outcome (observational epidemiology), identifying effective management for RMDs (clinical trials and evidence synthesis), and designing optimal delivery of care (health services research). He and his research team have particular expertise in common complex conditions (including musculoskeletal pain and fatigue, fibromyalgia, and early osteoarthritis), inflammatory conditions, and rare diseases. The programme hosts several UK-wide disease and drug registries: the British Society of Rheumatology Biologics Registers in Ankylosing Spondylitis (BSRBR-AS) and Psoriatic Arthritis (BSR-PsA) and the British Society for Antimicrobial Chemotherapy UK Antimicrobial Registry (UKAR).  Professor Macfarlane is a Chartered Statistician of the Royal Statistical Society, a Fellow of the Faculty of Public Health Medicine and an Honorary fellow of the Faculty of Occupational Medicine. 

External Memberships

• Health and Safety Executive (UK) Scientific Quality Advisory Group: Member
• British Pain Society Annual Scientific Meeting Organising Committee: Member
• NHS Research Scotland Deputy Clinical Lead for Pain
• Versus Arthritis Fellowship Committee: Member 
• British Society for Rheumatology: Research and Registers Committee 
• NIHR Senior Investigator

Prizes and Awards

Sir Alexander Morison Medal from the Royal College of Physicians of Edinburgh

Heberden Medal from the British Society for Rheumatology (2024)

Ernestine Henry Lecture (Faculty of Occupational Medicine Conference, 2024)

Research Overview

My major research interests are in the Epidemiology of Rheumatic and Musculoskeletal Disorders (RMD) with a particular focus on common disabling symptoms (chronic pain, and fatigue) inflammatory and non-inflammatory arthritis. I am Director of the Versus Arthritis and MRC Centre for Musculoskeletal Health and Work. I lead several nationwide drug registries. I have current live grant income over £10 million. 

Collaborations

Professor Macfarlane is Director of the MRC/Versus Arthritis Centre for Musculoskeletal Health and Work. Coordinated by the 51cg, the centre brings together fifteen different academic institutions across the UK, with interest and expertise in rheumatic and musculoskeletal disease, and its relation to occupation, to identify effective and cost-effective ways to minimise the adverse impacts of musculoskeletal disorders in the workplace. The work at the 51cg is focussed on investigating: media campaigns for low back pain; axial spondyloarthritis; pain management. 

European League Against Rheumatism (EULAR) revised guidelines for the management of fibromyalgia

Professor Macfarlane chaired an international group of clinicians, allied health professionals and scientists from 12 countries across Europe, in revising EULAR guidelines for the management of fibromyalgia. Since the original EULAR fibromyalgia guidelines, more than fifty randomised controlled trials have been published concerned with the phramcological or non-pharmacological management of the conditions. The revised guidelines were published, in 2016, in the Annals of the Rheumatic Diseases:

UK-RiME : UK Research in Musculoskeletal Epidemiology

The UK Research in Musculoskeletal Epidemiology (UK-RiME) partnership is a national collaboration between eight epidemiology centres in the United Kingdom including Aberdeen. The partnership seeks to develop a co-ordinated training programme facilitated by exchanges between departments at PhD, post-doctoral, NIHR academic clinical fellow, clinical fellow and international trainee levels.  UK-RiME facilitates access to one another’s cohorts and share analytical expertise with each other and the UK musculoskeletal research community.

Funding and Grants

• 2024-29/£1.2m/Versus Arthritis. “PrIOritising early detection of KNEE osteoaRthritis – PIOKNEER
• 2022-25/£999k/ Medical Research Council and Versus Arthritis Advanced Pain Discovery Platform. High Impact Chronic Pain and UK Biobank: presentation, transitions and targets for intervention
• 2022-24/£232k/Chief Scientist’s Office/ Supporting people with musculoskeletal disorders in Scotland to remain in work: adapting the Making it Work™ intervention developed for people with inflammatory arthritis in Canada (Co-Chief Investigator)
• 2021-25/£3,179k/MRC and Versus Arthritis/Consortium Against Pain inEquality (CAPE) - The impact of adverse childhood experiences on chronic pain and responses to treatment (Investigator and Work Package Lead)
• 2021-24/£485k /MRC/ Quantifying the Impact of Work on Paid Employment (Chief Investigator)
• 2021-26/£1,250k/British Society for Antimicrobial Chemotherapy/United Kingdom AntiMicrobial Registry (Co-chief Investigator)
• 2020-26/£2,488k/ NIHR/ NIHR Programme Grant: Development and evaluation of the Digital-My Arm Pain Programme (D-MAPP) for improving painful distal upper limb musculoskeletal disorders (Investigator)
• 2019-26/£2,300k/Medical Research Council & Versus Arthritis Centre of Excellence in Musculoskeletal Health and Work (Chief Investigator Investigator, Aberdeen)
• 2019-25/£1,138k/Versus Arthritis/Developing new models of care for people with fibromyalgia (PACFiND) (Chief Investigator)

Teaching Responsibilities

Postgraduate (PhD) research students

The Epidemiology group welcomes applications in our research areas of interest.

External courses

Professor Macfarlane established a week-long Intensive Course in Applied Epidemiology (ICAE) at the 51cg.  This course has been run here since 2007, having previously been run for 15 years at the University of Manchester.  The course is highly rated by attendees, with attendees from Europe, Asia, the Americas and Australasia.  The course is annual and starts on the first Monday in March. For further details and / or to register for the next course please see our .

The Epidemiology Group has also put on shorter courses at external locations including Warsaw and Bucharest and also runs courses focussed on specific clinical disciplines such as  "Essentials in Epidemiology for Reproductive Health".