51cg

Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

51cg
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the 51cg, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - 51cg 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available  on using instrumental variables in a surgery trial to address non-compliance. Collaborators were  (Oxford), (Lancaster), and (Manchester). 

Research on making trials more efficient, collaborating with . 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • The split-plot design was useful for evaluating complex, multi-level interventions but there is need for improvement in its design and report

    Goulão, B., MacLennan, G., Ramsay, C.
    Journal of Clinical Epidemiology, vol. 96, pp. 120-125
    Contributions to Journals: Articles
  • Systematic Techniques to Enhance rEtention in Randomised controlled trials: the STEER study protocol

    Gillies, K., Bower, P., Elliott, J., MacLennan, G., Newlands, R. S. N., Ogden, M., Treweek, S. P., Wells, M., Witham, M. D., Young, B., Francis, J. J.
    Trials, vol. 19, 197
    Contributions to Journals: Articles
  • How to resolve discrepancies when findings from randomized controlled trials and meta-analyses disagree?

    Sylvester, R., Canfield, S. E., Lam, T., Marconi, L., MacLennan, S., Yuan, Y., MacLennan, G., Norrie, J., Omar, M. I., Bruins, H. M., Hernández, V., Plass, K., Van Poppel, H., N'Dow, J.
    33rd Annual EAU Congress 2018
    Contributions to Conferences: Posters
  • Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial

    Constable, L., Cotterill, N., Cooper, D., Glazener, C., Drake, M. J., Forrest, M., Harding, C., Kilonzo, M., MacLennan, G., McCormack, K., McDonald, A., Mundy, A., Norrie, J., Pickard, R., Ramsay, C., Smith, R., Wileman, S., Abrams, P., The MASTER Study Group
    Trials, vol. 19, pp. 1-17
    Contributions to Journals: Articles
  • Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease and cancer: a systematic review and meta-analysis

    Ma, C., Avenell, A., Bolland, M., Hudson, J., Stewart, F., Robertson, C., Sharma, P., Fraser, C., MacLennan, G.
    BMJ, vol. 359, j4849
    Contributions to Journals: Articles
  • Bayesian clinical trial designs: Another option for trauma trials?

    Jansen, J. O., Pallmann, P., MacLennan, G., Campbell, M. K., UK-REBOA Trial Investigators
    The journal of trauma and acute care surgery, vol. 83, no. 4, pp. 736-741
    Contributions to Journals: Articles
  • THISTLE: trial of hands-on Interprofessional simulation training for local emergencies: a research protocol for a stepped-wedge clustered randomised controlled trial

    Lenguerrand, E., Winter, C., Innes, K., MacLennan, G., Siassakos, D., Lynch, P., Cameron, A., Crofts, J., McDonald, A., McCormack, K., Forrest, M., Norrie, J., Bhattacharya, S., Draycott, T., Thistle group
    BMC Pregnancy and Childbirth, vol. 17, 294
    Contributions to Journals: Articles
  • The SIMS trial: adjustable anchored single-incision mini-slings versus standard tension-free midurethral slings in the surgical management of female stress urinary incontinence. A study protocol for a pragmatic, multicentre, non-inferiority randomised controlled trial

    Abdel-Fattah, M., Maclennan, G., Kilonzo, M., Assassa, R. P., McCormack, K., Davidson, T., McDonald, A., N'Dow, J., Wardle, J., Norrie, J.
    BMJ Open, vol. 7, no. 8, pp. 1-18
    Contributions to Journals: Articles
  • Long-Term Randomized Trial of Intensive Versus Symptomatic Management in Paget's Disease of Bone: The PRISM-EZ Study

    Tan, A., Goodman, K., Walker, A., Hudson, J., MacLennan, G. S., Selby, P. L., Fraser, W. D., Ralston, S. H., PRISM-EZ Trial Group
    Journal of Bone and Mineral Research, vol. 32, no. 6, pp. 1165-1173
    Contributions to Journals: Articles
  • Conflict of Evidence: Resolving Discrepancies When Findings from Randomized Controlled Trials and Meta-analyses Disagree

    Sylvester, R. J., Canfield, S. E., Lam, T. B. L., Marconi, L., MacLennan, S., Yuan, Y., MacLennan, G., Norrie, J., Omar, M. I., Bruins, H. M., Hernandez, V., Plass, K., Van Poppel, H., N'Dow, J.
    European Urology, vol. 71, no. 5, pp. 811-819
    Contributions to Journals: Articles
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