51cg

People

Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

51cg
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the 51cg, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - 51cg 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available  on using instrumental variables in a surgery trial to address non-compliance. Collaborators were  (Oxford), (Lancaster), and (Manchester). 

Research on making trials more efficient, collaborating with . 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Economic evaluation of surgical treatments for women with stress urinary incontinence: a cost-utility and value of information analysis

    Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Becker, F., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
    BMJ Open, vol. 10, no. 6, 035555
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • IDENTIFY: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study

    Khadhouri, S., Gallagher, K. M., MacKenzie, K., Shah, T. T., Gao, C., Moore, S., Zimmermann, E., Edison, E., Jefferies, M., Nambiar, A., MacLennan, G., McGrath, J. S., Kasivisvanathan, V., IDENTIFY Protocol Collaborators Group
    International Journal of Surgery Protocols, vol. 21, pp. 8-12
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial

    Booth, J., Aucott, L., Cotton, S., Goodman, C., Hagen, S., Harari, D., Lawrence, M., Lowndes, A., Macaulay, L., MacLennan, G., Mason, H., McClurg, D., Norrie, J., Norton, C., O'Dolan, C., Skelton, D. A., Surr, C., Treweek, S.
    Trials, vol. 20, 723
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Practical help for specifying the target difference in sample size calculations for RCTs: The DELTA2 five-stage study, including a workshop

    Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., Maclennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
    Health Technology Assessment, vol. 23, no. 60
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Methods to deal with missing data in area under the curve outcomes in randomised controlled trials: the OPEN trial case

    Goulao, B., MacLennan, G.
    5th International Clinical Trials Methodology Conference, pp. 141-141
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • Laparoscopic supracervical hysterectomy versus endometrial ablation for women with heavy menstrual bleeding (HEALTH): a parallel-group, open-label, randomised controlled trial

    Cooper, K., Breeman, S., Scott, N. W., Scotland, G., Clark, J., Hawe, J., Hawthorn, R., Phillips, K., MacLennan, G., Wileman, S., McCormack, K., Hernández, R. A., Norrie, J., Bhattacharya, S., HEALTH Study Group
    The Lancet, vol. 394, no. 10207, pp. 1425-1436
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

    Brittenden, J., Cooper, D., Dimitrova, M., Scotland, G., Cotton, S. C., Elders, A., MacLennan, G., Ramsay, C. R., Norrie, J., Burr, J. M., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Tassie, E., Francis, J., Campbell, M. K.
    The New England Journal of Medicine, vol. 381, no. 10, pp. 912-922
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]
    • [ONLINE]
    • [ONLINE]

  • Photodynamic versus white light-guided treatment of non-muscle invasive bladder cancer: A study protocol for a randomised trial of clinical and cost-effectiveness

    Tandogdu, Z., Lewis, R., Duncan, A., Penegar, S., McDonald, A., Vale, L., Shen, J., Kelly, J. D., Pickard, R., N Dow, J., Ramsay, C., Mostafid, H., Mariappan, P., Nabi, G., Creswell, J., Lazarowicz, H., McGrath, J., Taylor, E., Clark, E., Maclennan, G., Norrie, J., Hall, E., Heer, R.
    BMJ Open, vol. 9, no. 9, e22268
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial

    Beard, D. J., Davies, L. J., Cook, J. A., MacLennan, G., Price, A., Kent, S., Hudson, J., Carr, A., Leal, J., Campbell, H., Fitzpatrick, R., Arden, N., Murray, D., Campbell, M. K., TOPKAT Study Group
    The Lancet, vol. 394, no. 10200, pp. 746-756
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds: Managing Adolescent first episode Psychosis: a feasibility study (MAPS)

    Pyle, M., Broome, M. R., Joyce, E., MacLennan, G., Norrie, J., Freeman, D., Fowler, D., Haddad, P. M., Shiers, D., Hollis, C., Smith, J., Liew, A., Byrne, R. E., French, P., Peters, S., Hudson, J., Davies, L., Emsley, R., Yung, A., Birchwood, M., Longden, E., Morrison, A. P.
    Trials, vol. 20, 395
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]
    • [ONLINE]
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