51cg

People

Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

51cg
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the 51cg, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - 51cg 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available  on using instrumental variables in a surgery trial to address non-compliance. Collaborators were  (Oxford), (Lancaster), and (Manchester). 

Research on making trials more efficient, collaborating with . 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

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  • Surgical interventions for women with stress urinary incontinence: systematic review and network meta-analysis of randomised controlled trials

    Imamura, M., Hudson, J., Wallace, S. A., MacLennan, G., Shimonovich, M., Omar, M. I., Javanbakht, M., Moloney, E., Becker, F., Ternent, L., Montgomery, I., Mackie, P., Saraswat, L., Monga, A., Vale, L., Craig, D., Brazzelli, M.
    BMJ, vol. 365, l1842
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
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    • [ONLINE]

  • Supporting Harm Reduction through Peer Support (SHARPS): Testing the feasibility and acceptability of a peer-delivered, relational intervention for people with problem substance use who are homeless, to improve health outcomes, quality of life and social functioning and reduce harms: Study protocol

    Parkes, T., Matheson, C., Carver, H., Budd, J., Liddell, D., Wallace, J., Pauly, B., Fotopoulou, M., Burley, A., Anderson, I., MacLennan, G., Foster, R.
    Pilot and Feasibility Studies, vol. 5, 64
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Surgical treatments for women with stress urinary incontinence: the ESTER systematic review and economic evaluation

    Brazzelli, M., Javanbakht, M., Imamura, M., Hudson, J., Moloney, E., Becker, F., Wallace, S., Omar, M. I., Shimonovich, M., MacLennan, G., Ternent, L., Vale, L., Montgomery, I., Mackie, P., Saraswat, L., Monga, A., Craig, D.
    Health Technology Assessment, vol. 23, no. 14, pp. 1-306
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]
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  • 399 - Surgical treatment for recurrent bulbar urethral stricture: A randomised open label superiority trial of open urethroplasty versus endoscopic urethrotomy (The OPEN Trial): Abstracts EAU19 – 34th Annual EAU Congress

    Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Cook, J., McColl, E., Breckons, M., Vale, L., Forbes, R., Currer, S., Forrest, M., Wilkinson, J., Andrich, D., Barclay, S., Munday, A., N’Dow, J., Payne, S., Watkin, N., Pickard, R.
    European Urology Supplements, vol. 18, no. 1, pp. e523
    Contributions to Journals: Articles
    • [ONLINE]
    • [ONLINE] DOI:

  • Cognitive-behavioural therapy for clozapine-resistant schizophrenia: the FOCUS RCT

    Morrison, A. P., Pyle, M., Gumley, A., Schwannauer, M., Turkington, D., MacLennan, G., Norrie, J., Hudson, J., Bowe, S., French, P., Hutton, P., Byrne, R., Syrett, S., Dudley, R., McLeod, H. J., Griffiths, H., Barnes, T. R., Davies, L., Shields, G., Buck, D., Tully, S., Kingdon, D.
    Health Technology Assessment, vol. 23, no. 7, pp. 1-144
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Open randomised trial of the (Arabin) pessary to prevent preterm birth in twin pregnancy with health economics and acceptability: STOPPIT-2-a study protocol

    Norman, J. E., Norrie, J., Maclennan, G., Cooper, D., Whyte, S., Burley, S. C., Smith, J. B., Shennan, A., Robson, S. C., Thornton, S., Kilby, M. D., Marlow, N., Stock, S. J., Bennett, P. R., Denton, J.
    BMJ Open, vol. 8, no. 12, e026430
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
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  • Protocol for a multicentre randomised controlled parallel-group trial to compare the effectiveness of remotely delivered cognitive-behavioural and graded exercise interventions with usual care alone to lessen the impact of fatigue in inflammatory rheumatic diseases (LIFT)

    Martin, K. R., Bachmair, E., Aucott, L., Dures, E., Emsley, R., Gray, S. R., Hewlett, S., Kumar, V., Lovell, K., Macfarlane, G. J., MacLennan, G., McNamee, P., Norrie, J., Paul, L., Ralston, S., Siebert, S., Wearden, A., White, P. D., Basu, N.
    BMJ Open, vol. 9, no. 1, e026793
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
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  • Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation

    Avenell, A., Robertson, C., Skea, Z., Jacobsen, E., Boyers, D., Cooper, D., Aceves-Martins, M., Retat, L., Fraser, C., Aveyard, P., Stewart, F., MacLennan, G., Webber, L., Corbould, E., Xu, B., Jaccard, A., Boyle, B., Duncan, E., Shimonovich, M., de Bruin, M.
    Health Technology Assessment, vol. 22, no. 68, pp. 1-286
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Contrast-enhanced ultrasound and/or colour duplex ultrasound for surveillance after endovascular abdominal aortic aneurysm repair: a systematic review and economic evaluation

    Brazzelli, M., Hernández, R., Sharma, P., Robertson, C., Shimonovich, M., MacLennan, G., Fraser, C., Jamieson, R., Vallabhaneni, S. R.
    Health Technology Assessment, vol. 22, no. 72, pp. 1-220
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

    Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., MacLennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
    BMJ, vol. 363, k3750
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
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