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People

Dr Lynda Constable

Dr Lynda Constable
Dr Lynda Constable
Dr Lynda Constable

BSc (Hons), PhD

Senior Trial Manager

51cg
Email Address
l.constable@abdn.ac.uk
School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am a Senior Trials Manager working across the portfolio of clinical trials at the Centre for Healthcare Randomised Trials (CHaRT) clinical trials unit (CTU) within the Aberdeen Centre for Evaluation (ACE, formerly Health Services Research Unit (HSRU)). 

I have worked as the lead trial manager on the CHESS, PIP, , CATHETER II, ,  and  trials.

I graduated with a BSc in Biosciences and Chemistry and a PhD in Cancer cell and Molecular biology. Prior to joining the unit, I worked as a Research Fellow at Aberdeen University on a range of projects with an emphasis on cancer biomarkers.

External Memberships

Member of the Executive Committee of the UK Trial Managers Network (UKTMN)

Member of the Education Committee for the Society for Clinical Trials (2013 - 2020)

Chair of the Education Committee for the Society for Clinical Trials (2018-2019)

Co-Chair of the Education Committee for the Society for Clinical Trials (2017-2018)

Chair of the Webinar Committee for the Society for Clinical Trials (2017-2018)

Member of the Board of Directors for the Society for Clinical Trials (2016)

Latest Publications

  • 24 months outcomes from the non-inferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery

    Constable, L., Drake, M. J., Cooper, D., MacLennan, G., Harding, C., Mundy, A., McCormack, K., Norrie, J., Ramsay, C., Smith, R., Cotterill, N., Kilonzo, M., Abrams, P., MASTER trial team
    European Urology Focus
    Contributions to Journals: Articles

  • Comparing the clinical and cost-effectiveness of various washout policies in preventing catheter associated complications in adults living with long-term catheters: synopsis of the CATHETER II RCT

    Johnson, D., Tripathee, S., Cooper, D., Constable, L., Omar, M. I., MacLennan, S., Cotton, S., Dimitropoulos, K., Evans, S., Hashim, H., Kilonzo, M., Larcombe, J., Little, P., MacLennan, G., Murchie, P., Kyaw Myint, P., N'Dow, J., Norrie, J., Paterson, C., Powell, K., Scotland, G., Thiruchelvam, N., Young, A., Abdel-fattah, M.
    Health Technology Assessment, vol. 30, no. 26
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Clinical and cost-effectiveness of medical management versus surgery for deep infiltrating endometriosis: synopsis from the DIAMOND RCT

    Cooper, K., Constable, L., Vadiveloo, T., Matuluko, A., Kennedy, C., McCann, S., Cotton, S., Gillies, K., Bruce, R., Smith, P., MacLennan, G., Clark, T. J.
    Health Technology Assessment, vol. 30, no. 62, pp. 437-464
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Protocol for a feasibility randomized control trial of the Supporting Toddlers with a connection to autism or ADHD to develop Strong Attention, Regulation, and Thinking skills (START) programme

    Hendry, A., Nosyk, M., Hulks, V., Hudson, J., Constable, L., Charman, T., Mathers, S., Rhodes, S., Scerif, G.
    Pilot and Feasibility Studies, vol. 11, no. 1, 122
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Supporting the professional development of trial managers: how can you help?

    Mitchell, E. J., Arundel, C., Babalis, D., Connolly, S., Constable, L., Goodman, K., Stylianou, L., Taylor, J., Wakefield, N., Williams, S., Wolstenhulme, F.
    Trials, vol. 26, no. 1, 436
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

View My Publications

Research

Research Overview

Clinical trials methodology

Clinical trial management

Research Areas

Applied Health Sciences

View Research Area

Current Research

Trial: Vault or Uterine prolapse surgery evaluation: Two parallel randomised controlled trials of surgical options for upper compartment (vault or uterine) pelvic organ prolapse.

Trial: investigating the surgical treatment of male stress incontinence after prostate surgery.

: Achieving Self-Directed Integrated Cancer Aftercare (ASICA) in melanoma: A randomised patient-focused trial of delivering the ASICA intervention as a means to earlier detection of recurrent and second primary melanoma

CATHETER II Trial: evaluating the effect of weekly saline or acidic prophylactic catheter washout policies with standard care on catheter related complications.

Teaching

Teaching Responsibilities

I have supervised a number of BSc and MSc student research projects, including topics such as understanding patient's decision making to participate in clinical trials; rapid introduction of new cancer therapies; personalised cancer therapies; and investigation of the mode of action novel cancer therapeutics.

Publications

Page 3 of 4 Results 21 to 30 of 38

  • Providing trial results to participants in Phase III pragmatic effectiveness RCTs: a scoping review

    Bruhn, H., Cowan, E., Campbell, M., Constable, L., Cotton, S., Entwistle, V., Humphreys, R., Innes, K., Jayacodi, S., Jayacodi, S., Knapp, P., South, A., Gillies, K.
    Trials, vol. 22, 361
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • It is unprecedented: trial management during the COVID-19 pandemic and beyond

    Mitchell, E. J., Ahmed, K., Breeman, S., Cotton, S., Constable, L., Ferry, G., Goodman, K., Hickey, H., Meakin, G., Mironov, K., Quann, N., Wakefield, N., McDonald, A.
    Trials, vol. 21, pp. 784
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • How to Deal with a Temporary Suspension and Restarting Your Trial: Our Experiences and lessons Learnt

    Constable, L., Davidson, T., Breeman, S., Cotton, S., McDonald, A., Wileman, S., Norrie, J.
    Trials, vol. 21, no. 1, pp. 765
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Using systematic data categorisation to quantify the types of data collected in clinical trials: the DataCat project

    Crowley, E., Treweek, S., Banister, K., Breeman, S., Constable, L., Cotton, S., Duncan, A., El Feky, A., Gardner, H., Goodman, K., Lanz, D., McDonald, A., Ogburn, E., Starr, K., Stevens, N., Valente, M., Fernie, G.
    Trials, vol. 21, no. 1, pp. 535
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Verifying participant-reported clinical outcomes: challenges and implications

    Breeman, S., Constable, L., Duncan, A., Starr, K., McDonald, A., Wileman, S., Cotton, S.
    Trials, vol. 21, no. 1, pp. 241
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Surgical interventions for uterine prolapse and for vault prolapse: the two VUE RCTs

    Hemming, C., Constable, L., Goulao, B., Kilonzo, M., Boyers, D., Elders, A., Cooper, K., Smith, A., Freeman, R. M., Breeman, S., McDonald, A., Hagen, S., Montgomery, I., Norrie, J., Glazener, C.
    Health Technology Assessment, vol. 24, no. 13, pp. vii-xxxi, 1-220
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Caspase-independence and characterization of bisnaphthalimidopropyl spermidine induced cytotoxicity in HL60 cells

    Bestwick, C. S., Milne, L., Dance, A. M., Cochennec, G., Cruickshank, G., Allain, E., Constable, L., Duthie, S. J., Thoo Lin, P. K.
    Toxicology in Vitro, vol. 52, pp. 342-350
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Male synthetic sling versus artificial urinary sphincter trial for men with urodynamic stress incontinence after prostate surgery (MASTER): Study protocol for a randomised controlled trial

    Constable, L., Cotterill, N., Cooper, D., Glazener, C., Drake, M. J., Forrest, M., Harding, C., Kilonzo, M., MacLennan, G., McCormack, K., McDonald, A., Mundy, A., Norrie, J., Pickard, R., Ramsay, C., Smith, R., Wileman, S., Abrams, P., The MASTER Study Group
    Trials, vol. 19, pp. 1-17
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Two parallel, pragmatic, UK multicentre, randomised controlled trials comparing surgical options for upper compartment (vault or uterine) pelvic organ prolapse (the VUE Study): study protocol for a randomised controlled trial

    Glazener, C., Constable, L., Hemming, C., Breeman, S., Elders, A., Cooper, K., Freeman, R., Smith, A. R. B., Hagen, S., McDonald, A., McPherson, G., Montgomery, I., Kilonzo, M., Boyers, D., Goulao, B., Norrie, J.
    Trials, vol. 17, pp. 1-18
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • How effective is mesh in pelvic organ prolapse surgery? An updated systematic review of randomised controlled trials

    Stewart, F., Constable, L. D., Cruickshank, M., Robertson, C., Glazener, C. M. A.
    Neurourology and Urodynamics, vol. 35, no. Suppl., pp. S299
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:
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