51cg

People

Dr Louie Van de Lagemaat

Dr Louie Van de Lagemaat
Dr Louie Van de Lagemaat
Dr Louie Van de Lagemaat

Bioinformatician

51cg
Office Address
2.26 Institute of Medical Sciences
Foresterhill Campus
Ashgrove Road West
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Louie van de Lagemaat joined the Centre for Genome-Enabled Biology and Medicine as a bioinformatician in October 2021. He completed his PhD in Genetics at the University of British Columbia, Canada in 2006. Subsequent positions focused on diverse subjects, including molecular neuroscience of the mammalian excitatory synapse and developmental and malignant haematopoiesis. He has used varied analytical methods such as linear and mixed effects models and has broad experience with short-read sequencing technologies including ChIP-seq, bulk and low-cell-count RNA-seq, mRNA splicing, ribosomal profiling (Ribo-seq), transcript methylation (meRIP-seq), poly-A tail length (tail-seq) and transcript half-life (SLAM-seq). He has also performed analysis of survival and loss of HLA allele heterozygosity in cancers.

Research

Research Specialisms

  • Genomics
  • Behavioural Biology
  • Bioinformatics

Our research specialisms are based on the Higher Education Classification of Subjects (HECoS) which is , published under the licence.

Publications

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  • Clustered coding variants in the glutamate receptor complexes of individuals with schizophrenia and bipolar disorder

    Frank, R. A. W., McRae, A. F., Pocklington, A. J., van de Lagemaat, L. N., Navarro, P., Croning, M. D. R., Komiyama, N. H., Bradley, S. J., Challiss, R. A. J., Armstrong, J. D., Finn, R. D., Malloy, M. P., MacLean, A. W., Harris, S. E., Starr, J. M., Bhaskar, S. S., Howard, E. K., Hunt, S. E., Coffey, A. J., Ranganath, V., Deloukas, P., Rogers, J., Muir, W. J., Deary, I. J., Blackwood, D. H., Visscher, P. M., Grant, S. G. N.
    PloS ONE, vol. 6, no. 4, e19011
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Characterization of the proteome, diseases and evolution of the human postsynaptic density.

    Bayés, ?., van de Lagemaat, L., Collins, M. O., Croning, M., Whittle, I., choudhary, j., Grant, S.
    Nature Neuroscience, vol. 14, pp. 19-21
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Genome variation and complexity in the autism spectrum

    van de Lagemaat, L. N., Grant, S. G. N.
    Neuron, vol. 67, no. 1, pp. 8-10
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Confirmed rare copy number variants implicate novel genes in schizophrenia

    Tam, G. W. C., van de Lagemaat, L. N., Redon, R., Strathdee, K. E., Croning, M. D. R., Malloy, M. P., Muir, W. J., Pickard, B. S., Deary, I. J., Blackwood, D. H. R., Carter, N. P., Grant, S. G. N.
    Biochemical Society Transactions, vol. 38, no. 2, pp. 445-451
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements

    Zhang, Y., Maksakova, I. A., Gagnier, L., van de Lagemaat, L. N., Mager, D. L.
    PLoS Genetics, vol. 4, no. 2, pp. e1000007
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Repeated recruitment of LTR retrotransposons as promoters by the anti-apoptotic locus NAIP during mammalian evolution

    Romanish, M. T., Lock, W. M., van de Lagemaat, L. N., Dunn, C. A., Mager, D. L.
    PLoS Genetics, vol. 3, no. 1, pp. e10
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Transcription of two human genes from a bidirectional endogenous retrovirus promoter

    Dunn, C. A., Romanish, M. T., Gutierrez, L. E., van de Lagemaat, L. N., Mager, D. L.
    Gene, vol. 366, no. 2, pp. 335-342
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line

    Maksakova, I. A., Romanish, M. T., Gagnier, L., Dunn, C. A., van de Lagemaat, L. N., Mager, D. L.
    PLoS Genetics, vol. 2, no. 1, pp. e2
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Multiple effects govern endogenous retrovirus survival patterns in human gene introns

    van de Lagemaat, L. N., Medstrand, P., Mager, D. L.
    Genome Biology, vol. 7, no. 9, pp. R86
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Endogenous retrovirus long terminal repeats as ready-to-use mobile promoters: the case of primate beta3GAL-T5

    Dunn, C. A., van de Lagemaat, L. N., Baillie, G. J., Mager, D. L.
    Gene, vol. 364, pp. 2-12
    Contributions to Journals: Articles
    • [ONLINE] DOI:
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