51cg

People

Dr Roger Staff

Dr Roger Staff
Dr Roger Staff
Dr Roger Staff

BSc MSc PhD MIPEM

Honorary Professor

51cg
Email Address
r.staff@abdn.ac.uk
Office Address

Nuclear Medicine ARI Foresterhill Aberdeen AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

Roger Staff was born in London and studied physics at UEA.  He moved to Aberdeen in 1988 and completed his PhD in medical physics in 1994.  He has worked for the NHS since 1991 and currently leads the clinical physics imaging team at NHS-Grampian. His other interests include Intelligence and social mobility.

Research

Research Overview

(Since 1999) founding member of the Aberdeen 1921 & 1936 birth cohort study group with three critical responsibilities for (1) hypothesis generation and hypothesis testing; (2) brain imaging and image analysis; (3) Advance data modelling of complex databases; (Since 2003 with Taurx) the imaging the effects tau aggregation inhibition and the use of surrogate imaging measures in drug development; (Since 2008) the development of structural and temporal (fMRI) complexity measures for use in ageing and neurodegenerative disease; (Since 2012) The prognostic value of automated analysis of sequential retinal images in diabetic retinopathy. The use of external quality assurance programs in diabetic retinopathy.   

Publications

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  • Genetic and environmental factors in late onset dementia: possible role for early parental death

    Whalley, L. J., Staff, R. T., Murray, A. D., Deary, I. J., Starr, J. M.
    International Journal of Geriatric Psychiatry, vol. 28, no. 1, pp. 75-81
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Brain structural complexity and life course cognitive change

    Mustafa, N., Ahearn, T. S., Waiter, G. D., Murray, A. D., Whalley, L. J., Staff, R. T.
    Neuroimage, vol. 61, no. 3, pp. 694-701
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Do brain image databanks support understanding of normal ageing brain structure?: A systematic review

    Dickie, D. A., Job, D. E., Poole, I., Ahearn, T. S., Staff, R. T., Murray, A. D., Wardlaw, J. M.
    European Radiology, vol. 22, no. 7, pp. 1385-1394
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Anticholinergic drugs in late life: adverse effects on cognition but not on progress to dementia

    Whalley, L. J., Sharma, S., Fox, H. C., Murray, A. D., Staff, R. T., Duthie, A. C., Deary, I. J., Starr, J. M.
    Journal of Alzheimer's Disease, vol. 30, no. 2, pp. 253-261
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Childhood socioeconomic status and adult brain size: Childhood socioeconomic status influences adult hippocampal size

    Staff, R. T., Murray, A. D., Ahearn, T. S., Mustafa, N., Fox, H. C., Whalley, L. J.
    Annals of Neurology, vol. 71, no. 5, pp. 653-660
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Brain lesions, hypertension and cognitive aging in the 1921 and 1936 Aberdeen birth cohorts

    Murray, A. D., Staff, R. T., McNeil, C. J., Salarirad, S., Starr, J. M., Deary, I. J., Whalley, L. J.
    Age, vol. 34, no. 2, pp. 451-459
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • The balance between cognitive reserve and brain imaging biomarkers of cerebrovascular and Alzheimer's diseases

    Murray, A. D., Staff, R. T., McNeil, C. J., Salarirad, S., Ahearn, T. S., Mustafa, N., Whalley, L. J.
    Brain, vol. 134, no. 12, pp. 3687-3696
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Inter-individual differences in fMRI entropy measurements in old age

    Sokunbi, M. O., Staff, R. T., Waiter, G. D., Ahearn, T. S., Fox, H. C., Deary, I. J., Starr, J. M., Whalley, L. J., Murray, A. D.
    IEEE Transactions on Biomedical Engineering, vol. 58, no. 11, pp. 3206-3214
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Regional cerebral blood flow and aberrant motor behaviour in Alzheimer's disease

    Reilly, T. J., Staff, R. T., Ahearn, T. S., Bentham, P., Wischik, C. M., Murray, A. D.
    Behavioural Brain Research, vol. 222, no. 2, pp. 375-379
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Childhood intelligence and brain white matter hyperintensities predict fluid intelligence age 78-81 years: a 1921 Aberdeen birth cohort study

    Salarirad, S., Staff, R. T., Fox, H. C., Deary, I. J., Whalley, L., Murray, A. D.
    Age and Ageing, vol. 40, no. 5, pp. 562-567
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • How the 1932 and 1947 mental surveys of Aberdeen schoolchildren provide a framework to explore the childhood origins of late onset disease and disability

    Whalley, L. J., Murray, A. D., Staff, R. T., Starr, J. M., Deary, I. J., Fox, H. C., Lemmon, H., Duthie, S. J., Collins, A. R., Crawford, J. R.
    Maturitas, vol. 69, no. 4, pp. 365-372
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Cerebellar brain volume accounts for variance in cognitive performance in older adults

    Hogan, M. J., Staff, R. T., Bunting, B. P., Murray, A. D., Ahearn, T. S., Deary, I. J., Whalley, L. J.
    Cortex, vol. 47, no. 4, pp. 441-450
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • The cerebral blood flow correlates of emotional facial processing in mild Alzheimer's disease

    Staff, R., Ahearn, T. S., Phillips, L. H., Cooper, C. L., Mowat, D., Wischik, C. M., Whalley, L. J., Murray, A. D.
    Neuroscience & Medicine, vol. 2, no. 1, pp. 6-13
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • The use of FDG-PET in assessing axillary lymph node status in breast cancer: a systematic review and meta-analysis of the literature

    Peare, R., Staff, R. T., Heys, S. D.
    Breast Cancer Research and Treatment, vol. 123, no. 1, pp. 281-290
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Brain volume and survival from age 78 to 85: the contribution of Alzheimer-type magnetic resonance imaging findings

    Staff, R. T., Murray, A. D., Ahearn, T., Salarirad, S., Mowat, D., Starr, J. M., Deary, I. J., Lemmon, H., Whalley, L. J.
    Journal of the American Geriatrics Society, vol. 58, no. 4, pp. 688-695
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Approximate entropy fMRI differences associated with cognitive decline

    Roijals Miras, J., Staff, R., Waiter, G. D., Murray, A. D., Fox, H. C., Starr, J., Deary, I. J., Whalley, L.
    Neuroimage, vol. 47, no. Supplement 1, pp. S102
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • Shape analysis of 123I-N-ω-fluoropropyl-2-β-carbomethoxy-3β-(4-iodophenyl) nortropane single-photon emission computed tomography images in the assessment of patients with parkinsonian syndromes

    Staff, R. T., Ahearn, T. S., Wilson, K., Counsell, C. E., Taylor, K., Caslake, R., Davidson, J. E., Gemmell, H. G., Murray, A. D.
    Nuclear Medicine Communications, vol. 30, no. 3, pp. 194-201
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Monitoring primary breast cancer throughout chemotherapy using FDG-PET

    McDermott, G. M., Welch, A., Staff, R. T., Gilbert, F. J., Schweiger, L. F., Semple, S. I. K., Smith, T. A. D., Hutcheon, A. W., Miller, I. D., Smith, I. C., Heys, S. D.
    Breast Cancer Research and Treatment, vol. 102, no. 1, pp. 75-84
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Baseline MRI delivery characteristics predict change in invasive ductal breast carcinoma PET metabolism as a result of primary chemotherapy administration

    Semple, S. I. K., Staff, R. T., Heys, S. D., Redpath, T. W., Welch, A., Ahearn, T. S., Hutcheon, A. W., Gilbert, F. J.
    Annals of Oncology, vol. 17, pp. 1393-1398
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Generality and specificity in cognitive aging: a volumetric brain analysis

    Staff, R. T., Murray, A. D., Deary, I. J., Whalley, L. J.
    Neuroimage, vol. 30, no. 4, pp. 1433-1440
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • A55 A rCBF study of hallucinations in dementia.

    Staff, R. T., Benjamin, K. D., Murray, A. D., Gemmell, H. G., Wischik, C. M.
    Nuclear Medicine Communications, vol. 27, no. 3, 295
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • Predicting response using MRI enhancement characteristics when response is determined by using change in enhancement pattern

    Staff, R. T., Semple, S. I. K., Ahearn, T. S., Redpath, T. W.
    Breast Cancer Research and Treatment, vol. 97, pp. 111-111
    Contributions to Journals: Letters
    • [ONLINE] DOI:

  • Brain white matter hyperintensities: Relative importance of different vascular risk factors in non-demented elderly people

    Murray, A. D., Staff, R. T., Shenkin, S. D., Deary, I. J., Starr, J. M., Whalley, L. J.
    Radiology, vol. 237, no. 1, pp. 251-257
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • The use of the Levenberg-Marquardt curve-fitting algorithm in pharmacokinetic modelling of DCE-MRI data

    Ahearn, T. S., Staff, R. T., Redpath, T. W., Semple, S. I. K.
    Physics in Medicine and Biology, vol. 50, no. 9, pp. N85-N92
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • FPCIT.net: a web based archive for use with 123I ioflupane

    Staff, R. T., Murray, A. D., Ahearn, T. S., Counsell, C. E., Taylor, K. S. M., Wilson, K., Gemmell, H. ..
    Nuclear Medicine Communications, vol. 26, P38
    Contributions to Journals: Abstracts
    • [ONLINE]
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