Dr Wenbo Zhan | The 51cg

Dr Wenbo Zhan

Lecturer

51cg

Email Address

w.zhan@abdn.ac.uk

Office Address

R353, Fraser Noble Building

School of Engineering

King's College

51cg

Aberdeen AB24 3UE, UK

School/Department

School of Engineering

Biography

Wenbo Zhan is a Lecturer in Biomedical Engineering in the School of Engineering. He received his undergraduate degrees from Xi’an Jiaotong University in 2008 and a master degree from Harbin Institute of Technology in 2010. He graduated from Imperial College London with his PhD degree in 2014 and then worked as a project consultant at Imperial College London and a postdoctoral research fellow at the National University of Singapore until 2016. Prior to joining the 51cg in 2019, he was a research associate at Imperial College London.

Qualifications

PhD Chemical Engineering
2014 - Imperial College London
MSc Thermal Energy and Power Engineering
2010 - Harbin Institute of Technology
BEng Thermal Energy and Power Engineering
2008 - Xi'an Jiaotong University
BEc Finance
2008 - Xi'an Jiaotong Univerisity

External Memberships

Editorial Board member of , 07/2026-present
Editorial Advisory Board member of , 12/2022-present
Member of European Society of Biomechanics

Research

Research Overview

Dr Zhan's research centres on biomedical engineering. He develops multiphysics and AI-enabled models to study fluid and tissue mechanics and transport processes in biological and physiological systems, with an emphasis on revealing the biophysical mechanisms underlying disease progression and on developing personalised medicine and precision therapy.

Mass transfer in biological systems, focusing on advanced drug delivery systems and modalities
Biofluid mechanics, including haemodynamics and fluid transport in tissues
Tissue mechanics, with applications to soft biological tissues and disease modelling
Image-based modelling, integrating medical imaging with physics-based modelling approaches

Funding and Grants

M2M-Brain: Mechanics to medicine - biphasic biomechanics and fluid transport in the brain, European Society of Biomechanics, Co-I (01/08/2026-31/07/2028)
Injectable thermosensitive hydrogel for controlled drug release targeting resected glioblastoma, The Royal Society, PI (01/10/2024-30/09/2026)
HyWay: Hydrogen production from waste, European Union & EPSRC, Co-I (15/04/2024-14/04/2028)
Evaluation and optimisation of thermosensitive hydrogel for controllable drug delivery against brain tumour, The Royal Society of Edinburgh, PI (01/02/2023-30/09/2023)
Image-based modelling and optimisation of convection-enhanced delivery for combination therapy against heterogeneous human brain tumour, The Royal Society, PI (12/08/2022-11/08/2024)
Gender differences in sex hormone transport in abdominal aortic aneurysm, The Royal Society, PI (31/03/2022-30/03/2024)
Optimisation of infusion catheter posture for improving convection-enhanced drug delivery to brain cancer, Children with Cancer UK – Children's Brain Tumour Drug Delivery Consortium, PI (01/03/2022-30/09/2022)
Porescale modelling of drug transport in brain tumours, 51cg School of Engineering PhD studentship, PI (01/09/2021-31/08/2024)
Nanoparticle-embedded membranes for long-term bioactive SARS-CoV2 prevention, Grampian University Hospitals NHS Trust, Co-I (01/04/2021-31/03/2023)
Multifunctional liquid crystals stabilised by hydrogen-bonding and their integration in new devices for energy harvesting, conversion and storage, The Royal Society of Edinburgh, Co-I (23/10/2020-30/12/2021)

Teaching

Teaching Responsibilities

Module coordinator

EG20H7 - Fluid Mechanics 1
EG30H3 - Fluid Mechanics 2
EG555L - Modelling of Biological Systems

Module contributor

EG55M1/6E - Finite Element Methods

Previously delivered modules

EG504Q - Introduction to Engineering for Life Scientists
EG555J - Research Methods for Bioengineers
EG4578 - BEng Group Design Project (Chemical Engineering)
EG5565 - MEng Group Design Project (Chemical & Mechanical Engineering)

Publications

Update

51cg

Biography

Qualifications

External Memberships

Research Overview

Funding and Grants

Teaching Responsibilities

Module coordinator

Module contributor

Previously delivered modules

Anti-angiogenic effect on convection-enhanced delivery of cytotoxic drugs

Effect of brain tissue anisotropy on convection-enhanced delivery of nanoparticles encapsulated carmustine

Convection enhanced delivery of light responsive antigen capturing oxygen generators for chemo-phototherapy triggered adaptive immunity

Characterization of Transport Properties of Drugs in Brain Tissue Using Computational Fluid Dynamics

Particle velocity measurement of binary mixtures in the riser of a circulating fluidized bed by the combined use of electrostatic sensing and high-speed imaging

Enhanced penetration of pro-apoptotic and anti-angiogenic micellar nanoprobe in 3D multicellular spheroids for chemophototherapy

A pilot study of aortic hemodynamics before and after thoracic endovascular repair with a double-branched endograft

Effects of Focused-Ultrasound-and-Microbubble-Induced Blood-Brain Barrier Disruption on Drug Transport under Liposome-Mediated Delivery in Brain Tumour: a Pilot Numerical Simulation Study

Convection enhanced delivery of anti-angiogenic and cytotoxic agents in combination therapy against brain tumour

Convection Enhanced Delivery of Light Responsive Antigen Capturing Oxygen Generators for Photoimmunotherapy of Hypoxic Tumors

Effect of Enhanced Cerebrospinal Fluid Flow on Drug Penetration in Convection Enhanced Delivery

Development of Nanoparticles for Drug Delivery to Brain Tumor: The Effect of Surface Materials on Penetration Into Brain Tissue

Delivery of liposome encapsulated temozolomide to brain tumour: Understanding the drug transport for optimisation

Effect of tissue permeability and drug diffusion anisotropy on convection-enhanced delivery

Neurosurgical Convection Enhanced Drug Delivery: Experiments and Modelling

Optimising Nanoparticle Property and Treatment Regimen for Improving Convection Enhanced Delivery of Doxorubicin to Brain Tumour

Towards a multiphysics modelling framework for thermosensitive liposomal drug delivery to solid tumour combined with focused ultrasound hyperthermia

Transport of Chemotherapeutic Agents in Anisotropic Tissue under Convection Enhanced Delivery for Localised Treatment

Convection enhanced delivery of liposome encapsulated doxorubicin for brain tumour therapy

Computational modelling of drug delivery to solid tumour: Understanding the interplay between chemotherapeutics and biological system for optimised delivery systems

Towards an Optimized Path Planner for the EDEN2020 Neurosurgical Steerable Needle

Convection enhanced delivery of chemotherapeutic drugs into brain tumour

3D-Bioprinting and Micro-/Nano-Technology: Emerging Technologies in Biomedical Sciences (Preface)

A Multiphysics Model for Focused Ultrasound Activated Thermosentitive Liposome Drug Delivery to Tumour

A Pilot Study on Aortic Flow before and after Endovascular Repair with a Novel Branched Stent-Graft for Thoracic Aortic Aneurysm

Mathematical Modelling of Cerebral Infusion of Nanoparticle Encapsulated Anticancer Drugs for Brain Tumour Therapy

Micromechanical Modelling of Brain White Matter

Numerical Simulation of Convection Enhanced Delivery of Nano Drug Carriers into Brain Tumour

Numerical Study on Cerebral Infusion Induced Backflow for Convection Enhanced Delivery

The effect of tumour size on drug transport and uptake in 3-D tumour models reconstructed from magnetic resonance images

Mathematical Modelling of Convection Enhanced Delivery of Carmustine and Paclitaxel for Brain Tumour Therapy

Model for Focused Ultrasound-mediated Thermosentitive Liposome Drug Delivery to Tumour

Numerical Simulation of Thermosensitive Liposome-mediated Delivery of Doxorubicin to Solid Tumour under High Intensity Focused Ultrasound Heating

Numerical Study on Convection Enhanced Delivery of Anticancer Drugs into Brain Tumour

A Dual Tracer 18F-FCH/18F-FDG PET Imaging of an Orthotopic Brain Tumor Xenograft Model

Numerical Simulation of Downdraft Biomass Gasifier: Influence of Structure Designs Using CFD Simulation

Numerical Study on the Hydrodynamics Behaviour in Bubbling Fluidized Bed for Sewage Sludge Gasification

The Effect of Infusion Position on Convection-Enhanced Delivery of Anticancer Drugs to Remnant Brain Tumour after Surgery

Drug Delivery to Solid Tumour with High Intensity Focused Ultrasound Heating

Effect of heterogeneous microvasculature distribution on drug delivery to solid tumour

Mathematical Modelling of Drug Transport and Uptake in a Realistic Model of Solid Tumour

Simulation of HIFU Heating in Solid Tumour: Comparison of Different Temperature Control Modes

A Mathematical Model for Thermosensitive Liposomal Delivery of Doxorubicin to Solid Tumour

Computational Study of Drug Transport in Realistic Models of Solid Tumour

Computational Study of Drug Transport in Realistic Models of Solid Tumour

Study on Hydrodynamic Characteristics in Liquid-Solid Reactor

Prediction on immersed tubes erosion using two-fluid model in a bubbling fluidized bed

Potential of Clean Development Mechanism Projects in Heilongjiang Province

Study of the impact of the velocity inlet boundary condition to the bubbling fluidized bed

Simulation of Particle Segregation Behavior in Bubbling Fluidized Bed

Refine

Chapters in Books, Reports and Conference Proceedings

Contributions to Conferences

Contributions to Journals