51cg

People

Professor Graeme MacLennan

Professor Graeme MacLennan
Professor Graeme MacLennan
Professor Graeme MacLennan

Director (CHaRT)

51cg
Email Address
g.maclennan@abdn.ac.uk
Telephone Number
+44 (0)1224 438147
Office Address

Health Services Research Unit
2nd Floor Health Sciences Building
Foresterhill
Aberdeen
AB25 2ZD

School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I am currently Professor of Medical Statistics and the Director of the Centre for Health Care Randomised Trials (CHaRT) which is the Clinical Trials Unit embedded within the Health Services Research Unit. My overarching research interest is in designing fair tests of health care treatments and policies, with a specifc interest in evaluating surgical and complex interventions. I'm also interested in improving the design, conduct, and analysis and reporting of clinical trials through the development and application of methodological research to clinical trials from CHaRT. 

My undergrad degree is in Mathematics from the 51cg, graduating in 1997. After a year training as a Mathematics teacher I joined the Unit in September 1998 as a statistician. I studied part-time for an MSc in Applied Statistics with Sheffield Hallam University, graduating in 2004. In 2008 I was appointed Senior Statistican, and in 2016 was I Interim Programme Director for the Health Care Assessment Programme, until being appointment as CHaRT Director in April 2017.  

Qualifications

  • BSc Mathematics 
    1997 - 51cg 
  • MSc Applied Statistics 
    2004 - Sheffield Hallam University 
Research

Research Overview

The application of statistical methods to clinical trials. Recent example is JCE paper available  on using instrumental variables in a surgery trial to address non-compliance. Collaborators were  (Oxford), (Lancaster), and (Manchester). 

Research on making trials more efficient, collaborating with . 

Current Research

A complete list of the CHaRT RCT portolio is available by clicking

Teaching

Teaching Responsibilities

I teach on our MPH course module PU5031: EVIDENCE-BASED HEALTH.

Publications

Page 5 of 12 Results 101 to 125 of 285

  • The arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: The STOPPIT 2 RCT

    Norman, J. E., Norrie, J., Maclennan, G., Cooper, D., Whyte, S., Chowdhry, S., Cunningham-Burley, S., Neilson, A. R., Mei, X. W., Smith, J. B., Shennan, A., Robson, S. C., Thornton, S., Kilby, M. D., Marlow, N., Stock, S. J., Bennett, P. R., Denton, J., on behalf of the STOPPIT collaborative group
    NIHR Health Technology Assessment programme. 94 pages
    Books and Reports: Other Reports
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Outcomes of a non-inferiority randomised controlled trial of surgery for men with urodynamic stress incontinence after prostate surgery (MASTER)

    Abrams, P., Constable, L., Cooper, D., MacLennan, G., Drake, M. J., Harding, C., Mundy, A., McCormack, K., McDonald, A., Norrie, J., Ramsay, C., Smith, R., Cotterill, N., Kilonzo, M., Glazener, C., MASTER trial team
    European Urology, vol. 79, no. 6, pp. 812-823
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Tibial nerve stimulation compared with sham to reduce incontinence in care home residents: ELECTRIC RCT

    Booth, J., Aucott, L., Cotton, S., Davis, B., Fenocchi, L., Goodman, C., Hagen, S., Harari, D., Lawrence, M., Lowndes, A., Macaulay, L., MacLennan, G., Mason, H., McClurg, D., Norrie, J., Norton, C., O'Dolan, C., Skelton, D., Surr, C., Treweek, S.
    Health technology assessment (Winchester, England), vol. 25, no. 41, pp. 1-109
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • TISU (Therepeutic Intervention for Stones in the Ureter): ESWL versus Ureteroscopy, a multicentre RCT

    Dasgupta, R., Cameron, S., Aucott, L., Maclennan, G., Thomas, R. E., N'dow, J., Norrie, J., Anson, K., Keeley, F. X., Maclennan, S., Starr, K., Mcclinton, S.
    European Urology, vol. 79, no. S1, pp. S390-S390
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:

  • Primary trabeculectomy for advanced glaucoma: pragmatic multicentre randomised controlled trial (TAGS)

    King, A., Hudson, J., Fernie, G., Kernohan, A., Azuara-Blanco, A., Burr, J., Homer, T., Shabaninejad, H., Sparrow, J. M., Garway-Heath, D., Barton, K., Norrie, J., McDonald, A., Vale, L., MacLennan, G., King, A., Agrawal, P., Stead, R., Broadway, D. C., Strouthidis, N., Chew, S., Sng, C., Toth, M., Gazzard, G., Elkarmouty, A., Nikita, E., Triolo, G., Aguilar-Munoa, S., Goyal, S., Lim, S., Sung, V., Masood, I., Wride, N., Sandhu, A., Hill, E., Sparrow, J., Grey, F., Bourne, R., Nithyanandarajah, G., Willshire, C., Bloom, P., Ahmed, F., Cordeiro, F., Crawley, L., Normando, E., Ameen, S., Tryfinopoulou, J., Porteous, A., Azuara-Blanco, A., Sidiki, S., TAGS Study Group
    BMJ, vol. 373, n1014
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Equity of access to critical care services in Scotland: A Bayesian spatial analysis

    Emerson, P., Green, D. R., Stott, S., Maclennan, G., Campbell, M. K., Jansen, J. O.
    Journal of the Intensive Care Society, vol. 22, no. 2, pp. 127-135
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Evaluation of the Arabin cervical pessary for prevention of preterm birth in women with a twin pregnancy and short cervix (STOPPIT-2): An open-label randomised trial and updated meta-analysis

    Norman, J. E., Norrie, J., MacLennan, G., Cooper, D., Whyte, S., Chowdhry, S., Cunningham-Burley, S., Mei, X. W., Smith, J. B. E., Shennan, A., Robson, S. C., Thornton, S., Kilby, M. D., Marlow, N., Stock, S. J., Bennett, P. R., Denton, J., STOPPIT-2 collaborative group
    PLoS Medicine, vol. 18, no. 3, e1003506
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Protocol for a randomised controlled trial comparing laparoscopic cholecystectomy with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones (C-Gall trial)

    Ahmed, I., Innes, K., Brazzelli, M., Gillies, K., Newlands, R., Avenell, A., Hernández, R., Blazeby, J., Croal, B., Hudson, J., MacLennan, G., McCormack, K., McDonald, A., Murchie, P., Ramsay, C.
    BMJ Open, vol. 11, no. 3, e039781
    Contributions to Journals: Articles
    • [ONLINE]
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Survey on ureTEric draiNage post uncomplicaTed ureteroscopy (STENT)

    Bhatt, N. R., MacKenzie, K., Shah, T. T., Gallagher, K., Clement, K., Cambridge, W. A., Kulkarni, M., MacLennan, G., Manecksha, R. P., Wiseman, O. J., Mcclinton, S., Smith, D., Kasivisvanathan, V.
    BJUI Compass, vol. 2, no. 2, pp. 115-125
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Psychological intervention, antipsychotic medication or a combined treatment for adolescents with a first episode of psychosis: the MAPS feasibility three-arm RCT

    Morrison, A. P., Pyle, M., Byrne, R., Broome, M., Freeman, D., Johns, L., James, A., Husain, N., Whale, R., MacLennan, G., Norrie, J., Hudson, J., Peters, S., Davies, L., Bowe, S., Smith, J., Shiers, D., Joyce, E., Jones, W., Hollis, C., Maughan, D.
    Health technology assessment (Winchester, England), vol. 25, no. 4, pp. 1-124
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Open urethroplasty versus endoscopic urethrotomy for recurrent urethral stricture in men: the OPEN RCT

    Pickard, R., Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Breckons, M., Vale, L., Whybrow, P., Rapley, T., Forbes, R., Currer, S., Forrest, M., Wilkinson, J., McColl, E., Andrich, D., Barclay, S., Cook, J., Mundy, A., N'Dow, J., Payne, S., Watkin, N.
    Contributions to Journals: Registered Reports
    • [ONLINE] DOI:

  • Surgical Treatment for Recurrent Bulbar Urethral Stricture: A Randomised Open-label Superiority Trial of Open Urethroplasty Versus Endoscopic Urethrotomy (the OPEN Trial)

    Goulao, B., Carnell, S., Shen, J., MacLennan, G., Norrie, J., Cook, J., McColl, E., Breckons, M., Vale, L., Whybrow, P., Rapley, T., Forbes, R., Currer, S., Forrest, M., Wilkinson, J., Andrich, D., Barclay, S., Mundy, A., N'Dow, J., Payne, S., Watkin, N., Pickard, R.
    European Urology, vol. 78, no. 4, pp. 572-580
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Antipsychotic medication versus psychological intervention versus a combination of both in adolescents with first-episode psychosis (MAPS): a multicentre, three-arm, randomised controlled pilot and feasibility study

    Morrison, A. P., Pyle, M., Maughan, D., Johns, L., Freeman, D., Broome, M. R., Husain, N., Fowler, D., Hudson, J., MacLennan, G., Norrie, J., Shiers, D., Hollis, C., James, A., MAPS group
    The lancet. Psychiatry, vol. 7, no. 9, pp. 788-800
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Mesh inlay, mesh kit or native tissue repair for women having repeat anterior or posterior prolapse surgery: randomised controlled trial (PROSPECT)

    Glazener, C., Breeman, S., Elders, A., Hemming, C., Cooper, K. G., Freeman, R. M., Smith, A., Hagen, S., Montgomery, I., Kilonzo, M., Boyers, D., McDonald, A., McPherson, G., MacLennan, G., Norrie, J., Reid, F. M., PROSPECT study group
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 127, no. 8, pp. 1002-1013
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • The clinical and cost effectiveness of surgical interventions for stones in the lower pole of the kidney: the percutaneous nephrolithotomy, flexible ureterorenoscopy and extracorporeal shockwave lithotripsy for lower pole kidney stones randomised controlled trial (PUrE RCT) protocol

    McClinton, S., Starr, K., Thomas, R., MacLennan, G., Lam, T., Hernandez, R., Pickard, R., Anson, K., Clark, T., MacLennan, S., Thomas, D., Smith, D., Turney, B., McDonald, A., Cameron, S., Wiseman, O.
    Trials, vol. 21, 479
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Total versus partial knee replacement in patients with medial compartment knee osteoarthritis: the TOPKAT RCT

    Beard, D. J., Davies, L. J., Cook, J. A., MacLennan, G., Price, A., Kent, S., Hudson, J., Carr, A., Leal, J., Campbell, H., Fitzpatrick, R., Arden, N., Murray, D., Campbell, M. K.
    Health technology assessment (Winchester, England), vol. 24, no. 20, pp. 1-98
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Baseline Characteristics of Participants in the Treatment of Advanced Glaucoma Study: A Multicenter Randomized Controlled Trial

    King, A. J., Hudson, J., Fernie, G., Burr, J., Azuara-Blanco, A., Sparrow, J. M., Barton, K., Garway-Heath, D., Kernohan, A., MacLennan, G., TAGS Research Group
    American Journal of Ophthalmology, vol. 213, pp. 186-194
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Surgical treatments for women with stress urinary incontinence: a systematic review of economic evidence

    Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Imamura, M., Hudson, J., MacLennan, G., Vale, L., Craig, D.
    Systematic reviews , vol. 9, 85
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Effect of hands-on interprofessional simulation training for local emergencies in Scotland: the THISTLE stepped-wedge design randomised controlled trial

    Lenguerrand, E., Winter, C., Siassakos, D., MacLennan, G., Innes, K., Lynch, P., Cameron, A., Crofts, J., McDonald, A., McCormack, K., Forrest, M., Norrie, J., Bhattacharya, S., Draycott, T.
    BMJ Quality & Safety, vol. 29, no. 2, pp. 122-134
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]
    • [ONLINE]

  • Early signs monitoring to prevent relapse in psychosis and promote well-being, engagement, and recovery: Protocol for a feasibility cluster randomized controlled trial harnessing mobile phone technology blended with peer support

    Gumley, A., Bradstreet, S., Ainsworth, J., Allan, S., Alvarez-Jimenez, M., Beattie, L., Bell, I., Birchwood, M., Briggs, A., Bucci, S., Castagnini, E., Clark, A., Cotton, S. M., Engel, L., French, P., Lederman, R., Lewis, S., Machin, M., MacLennan, G., Matrunola, C., McLeod, H., McMeekin, N., Mihalopoulos, C., Morton, E., Norrie, J., Reilly, F., Schwannauer, M., Singh, S. P., Smith, L., Sundram, S., Thomson, D., Thompson, A., Whitehill, H., Wilson-Kay, A., Williams, C., Yung, A., Farhall, J., Gleeson, J.
    JMIR Research Protocols, vol. 9, no. 1, pp. e15058
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Economic evaluation of surgical treatments for women with stress urinary incontinence: a cost-utility and value of information analysis

    Javanbakht, M., Moloney, E., Brazzelli, M., Wallace, S., Ternent, L., Omar, M. I., Monga, A., Saraswat, L., Mackie, P., Becker, F., Imamura, M., Hudson, J., Shimonovich, M., MacLennan, G., Vale, L., Craig, D.
    BMJ Open, vol. 10, no. 6, 035555
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • IDENTIFY: The investigation and detection of urological neoplasia in patients referred with suspected urinary tract cancer: A multicentre cohort study

    Khadhouri, S., Gallagher, K. M., MacKenzie, K., Shah, T. T., Gao, C., Moore, S., Zimmermann, E., Edison, E., Jefferies, M., Nambiar, A., MacLennan, G., McGrath, J. S., Kasivisvanathan, V., IDENTIFY Protocol Collaborators Group
    International Journal of Surgery Protocols, vol. 21, pp. 8-12
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial

    Booth, J., Aucott, L., Cotton, S., Goodman, C., Hagen, S., Harari, D., Lawrence, M., Lowndes, A., Macaulay, L., MacLennan, G., Mason, H., McClurg, D., Norrie, J., Norton, C., O'Dolan, C., Skelton, D. A., Surr, C., Treweek, S.
    Trials, vol. 20, 723
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Practical help for specifying the target difference in sample size calculations for RCTs: The DELTA2 five-stage study, including a workshop

    Cook, J. A., Julious, S. A., Sones, W., Hampson, L. V., Hewitt, C., Berlin, J. A., Ashby, D., Emsley, R., Fergusson, D. A., Walters, S. J., Wilson, E. C., Maclennan, G., Stallard, N., Rothwell, J. C., Bland, M., Brown, L., Ramsay, C. R., Cook, A., Armstrong, D., Altman, D., Vale, L. D.
    Health Technology Assessment, vol. 23, no. 60
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Methods to deal with missing data in area under the curve outcomes in randomised controlled trials: the OPEN trial case

    Goulao, B., MacLennan, G.
    5th International Clinical Trials Methodology Conference, pp. 141-141
    Contributions to Journals: Abstracts
    • [ONLINE] DOI:
Show 10 | 25 | 50 | 100 results per page

Refine

Books and Reports

Chapters in Books, Reports and Conference Proceedings

Contributions to Conferences

Contributions to Journals

Update