51cg

People

Dr Seonaidh Cotton

Dr Seonaidh Cotton
Dr Seonaidh Cotton
Dr Seonaidh Cotton

BSc (Hons), MLitt, PhD

Head of Trial Management

51cg
Email Address
s.c.cotton@abdn.ac.uk
Telephone Number
+44 (0)1224 438178
Office Address
Aberdeen Centre for Evaluation, Third floor, Health Sciences Building
Foresterhill Campus
Foresterhill
AB25 2ZD

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School/Department
School of Medicine, Medical Sciences and Nutrition

Biography

I joined HSRU in 2007 as a trial manager.  I graduated from the 51cg with a BSc in Health Sciences in 1993, an MLitt in 1995, and a PhD in 2007.  Prior to joining the Unit, I worked in the Department of Public Health at the 51cg.

I am Head of Trial Management/Senior Trial Manager within CHaRT supporting the portfolio of trials.      

Previously I was the Deputy Senior Trial Manager and supported a number of studies including RAACENO, EMPOWER and ELECTRIC (all now completed).  I also worked as trial manager on a number of CHaRT trials, including ALLEGRO, BICS, TWICS, CLASS, NIAMI, FOCCUS, REFLUX and the Cysteamine in CF study.  

I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.

 

Qualifications

  • BSc Health Sciences 
    1993 - 51cg 
  • MLitt by research 
    1994 - 51cg 
  • PhD Public Health 
    2008 - 51cg 
Research

Research Overview

Trial methodology & trial management

Research Areas

Applied Health Sciences

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Nutrition and Health

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Current Research

I am the Senior Trial Manager within CHaRT supporting the portfolio of trials.   I also currently work on the BICS trial - a multicentre trial investigating the effectiveness of the beta-blocker bisoprolol in preventing exacerbations of chronic obstructive pulmonary disease.    

I am interested in methodological research that can be carried out alongside existing trials, including the provision of information to potential participants and strategies to increase response rates.

Past Research

Since joining the Unit I have worked on a number of trials that have now been completed. 

TWICS  - a multicentre trial investigating the effectiveness of low dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease.

CLASS - a multicentre trial comparing foam sclerotherapy and endovenous laser ablation with conventional surgery in patients with varicose veins;

NIAMI - a phase II multicentre trial investigating whether an intravenous injection of sodium nitrite given immediately before the infarct related artery is opened reduces ischaemia reperfusion injury in patients with myocardial infarction;

FOCCUS - a pragmatic multi-centred randomised controlled trial of surgical HDU care versus HDU care delivered in an ICU and pre-operative fluid loading in high-risk patients undergoing major elective surgery

REFLUX - a multi-centre randomised trial comparing a policy of relatively early laparoscopic surgery with a continued best medical management policy for people with more severe gastro-oesophageal reflux disease.

The Cysteamine in CF study - a single-centre, single group open label study of oral cysteamine in patients with Cystic Fibrosis.

I also supported RAACENO, EMPOWER and ELECTRIC (all now completed) as senior trial manager.

Teaching

Courses

Teaching Responsibilities

I have supervised a number of undergraduate and Masters level research projects, including topics such as provision of information to potential participants, strategies to increase response rates, and outcome measures.

 

 

Non-course Teaching Responsibilities

Outwith the University, I am a faculty member on the Edinburgh Clinical Trial Management Course ().

 

Publications

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  • The ALLEGRO trial: a placebo controlled randomised trial of intravenous lidocaine in accelerating gastrointestinal recovery after colorectal surgery

    Paterson, H., Cotton, S., Norrie, J., Nimmo, S., Foo, I., Balfour, A., Speake, D., MacLennan, G., Stoddart, A., Innes, K., Cameron, S., Aucott, L., McCormack, K.
    Trials, vol. 23, no. 1, 84
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Has the human papillomavirus (HPV) immunization programme improved obstetric outcomes in spontaneous delivery?: An ecological study

    Xu, X., Woolner, A., Bhattacharya, S., Cotton, S., Zhao, F., Cruickshank, M.
    European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 262, pp. 221-227
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Tibial nerve stimulation compared with sham to reduce incontinence in care home residents: ELECTRIC RCT

    Booth, J., Aucott, L., Cotton, S., Davis, B., Fenocchi, L., Goodman, C., Hagen, S., Harari, D., Lawrence, M., Lowndes, A., Macaulay, L., MacLennan, G., Mason, H., McClurg, D., Norrie, J., Norton, C., O'Dolan, C., Skelton, D., Surr, C., Treweek, S.
    Health technology assessment (Winchester, England), vol. 25, no. 41, pp. 1-109
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Providing trial results to participants in Phase III pragmatic effectiveness RCTs: a scoping review

    Bruhn, H., Cowan, E., Campbell, M., Constable, L., Cotton, S., Entwistle, V., Humphreys, R., Innes, K., Jayacodi, S., Jayacodi, S., Knapp, P., South, A., Gillies, K.
    Trials, vol. 22, 361
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Developing the INCLUDE Ethnicity Framework: a tool to help trialists design trials that better reflect the communities they serve

    Treweek, S., Banister, K., Bower, P., Cotton, S., Devane, D., Gardner, H., Isaacs, T., Nestor, G., Oshisanya, A., Parker, A., Rochester, L., Soulsby, I., Williams, H. C., Witham, M. D.
    Trials, vol. 22, 337
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • It is unprecedented: trial management during the COVID-19 pandemic and beyond

    Mitchell, E. J., Ahmed, K., Breeman, S., Cotton, S., Constable, L., Ferry, G., Goodman, K., Hickey, H., Meakin, G., Mironov, K., Quann, N., Wakefield, N., McDonald, A.
    Trials, vol. 21, pp. 784
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • How to Deal with a Temporary Suspension and Restarting Your Trial: Our Experiences and lessons Learnt

    Constable, L., Davidson, T., Breeman, S., Cotton, S., McDonald, A., Wileman, S., Norrie, J.
    Trials, vol. 21, no. 1, pp. 765
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Using systematic data categorisation to quantify the types of data collected in clinical trials: the DataCat project

    Crowley, E., Treweek, S., Banister, K., Breeman, S., Constable, L., Cotton, S., Duncan, A., El Feky, A., Gardner, H., Goodman, K., Lanz, D., McDonald, A., Ogburn, E., Starr, K., Stevens, N., Valente, M., Fernie, G.
    Trials, vol. 21, no. 1, pp. 535
    Contributions to Journals: Articles
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    • [OPEN ACCESS]
    • [ONLINE]

  • Verifying participant-reported clinical outcomes: challenges and implications

    Breeman, S., Constable, L., Duncan, A., Starr, K., McDonald, A., Wileman, S., Cotton, S.
    Trials, vol. 21, no. 1, pp. 241
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Trial Forge Guidance 2: how to decide if a further Study Within A Trial (SWAT) is needed

    Treweek, S., Bevan, S., Bower, P., Briel, M., Campbell, M., Christie, J., Collett, C., Cotton, S., Devane, D., El Feky, A., Galvin, S., Gardner, H., Gillies, K., Hood, K., Jansen, J., Littleford, R., Parker, A., Ramsay, C., Restrup, L., Sullivan, F., Torgerson, D., Tremain, L., von Elm, E., Westmore, M., Williams, H., Williamson, P. R., Clarke, M.
    Trials, vol. 21, 33
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Women’s Preferences for Communication with the Cervical Screening Programme: A Qualitative Study

    Ravindran, R., Cotton, S., Cruickshank, M.
    Cytopathology, vol. 31, no. 1, pp. 47-52
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • ELECtric Tibial nerve stimulation to Reduce Incontinence in Care homes: protocol for the ELECTRIC randomised trial

    Booth, J., Aucott, L., Cotton, S., Goodman, C., Hagen, S., Harari, D., Lawrence, M., Lowndes, A., Macaulay, L., MacLennan, G., Mason, H., McClurg, D., Norrie, J., Norton, C., O'Dolan, C., Skelton, D. A., Surr, C., Treweek, S.
    Trials, vol. 20, 723
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins

    Brittenden, J., Cooper, D., Dimitrova, M., Scotland, G., Cotton, S. C., Elders, A., MacLennan, G., Ramsay, C. R., Norrie, J., Burr, J. M., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Tassie, E., Francis, J., Campbell, M. K.
    The New England Journal of Medicine, vol. 381, no. 10, pp. 912-922
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]
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  • Low-dose oral theophylline combined with inhaled corticosteroids for people with chronic obstructive pulmonary disease and high risk of exacerbations: a RCT

    Devereux, G., Cotton, S., Fielding, S., McMeekin, N., Barnes, P. J., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., Soyza, A. D., Gompertz, S., Haughney, J., Innes, K., Kaniewska, J., Lee, A., Morice, A., Norrie, J., Sullivan, A., Wilson, A., Price, D.
    Health technology assessment (Winchester, England), vol. 23, no. 37, pp. 1-146
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Estimating Site Performance (ESP): can trial managers predict recruitment success at trial sites? An exploratory study

    Bruhn, H., Treweek, S., Duncan, A., Shearer, K., Cameron, S., Campbell, K., Innes, K., McRae, D., Cotton, S. C.
    Trials, vol. 20, 192
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]
    • [ONLINE]

  • Reducing Asthma Attacks in Children using Exhaled Nitric Oxide as a biomarker to inform treatment strategy: a randomised trial (RAACENO)

    Turner, S., Cotton, S. C., Emele, C. D., Thomas, R. E., Fielding, S. A., Gaillard, E. A., de Jongste, J. C., Morgan, H. M., Nielson, A. R., Norrie, J., Pijnenburg, M. W., Price, D. B., Thomas, M.
    Trials, vol. 20, 573
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [ONLINE]

  • Information needs of young women vaccinated against HPV attending colposcopy: a qualitative study

    Young, A., Cotton, S., Cruickshank, M. E.
    BMC Women's Health, vol. 18, no. 1, 200
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Effect of Theophylline as Adjunct to Inhaled Corticosteroids on Exacerbations in Patients With COPD: A Randomized Clinical Trial

    Devereux, G., Cotton, S., Fielding, S., McMeekin, N., Barnes, P. J., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., De Soyza, A., Gompertz, S., Haughney, J., Innes, K., Kaniewska, J., Lee, A., Morice, A., Norrie, J., Sullivan, A., Wilson, A., Price, D.
    JAMA, vol. 320, no. 15, pp. 1548-1559
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [ONLINE]

  • Relative importance of informational items in Participant Information Leaflets for trials: a Q-Methodology approach

    Innes, K. A., Cotton, S., Campbell, M. K., Elliott, J., Gillies, K.
    BMJ Open, vol. 8, no. 9, e023303
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Patient reported measures of informed consent for clinical trials: A systematic review

    Gillies, K., Duthie, A., Cotton, S., Campbell, M. K.
    PloS ONE, vol. 13, no. 6, e0199775
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Use of 'Low-Dose' Theophylline to Reduce Exacerbations of COPD: A Pragmatic Multicentre Randomised Placebo Controlled Trial

    Price, D. B., Cotton, S., Fielding, S., McMeekin, N., Barnes, P., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., De Soyza, A., Gompertz, S., Haughney, J., Lee, A., Morice, A., Norrie, J., Sullivan, A., Wilson, A., Devereux, G.
    American Thoracic Society 2018 International Conference, A7709
    Contributions to Journals: Abstracts
    • [ONLINE]
    • [OPEN ACCESS]

  • Trial Forge Guidance 1: What is a Study Within A Trial (SWAT)

    Treweek, S., Bevan, S., Bower, P., Campbell, M., Christie, J., Clarke, M., Collett, C., Cotton, S. C., Devane, D., El Feky, A., Flemyng, E., Galvin, S., Gardner, H. R., Gillies, K., Jansen, J., Littleford, R., Parker, A., Ramsay, C., Restrup, L., Sullivan, F., Torgerson, D., Tremain, L., Westmore, M., Williamson, P. R.
    Trials, vol. 19, 139
    Contributions to Journals: Letters
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • The influence of early research experience in medical school on the decision to intercalate and future career in clinical academia: A questionnaire study

    Boyle, S. E., Cotton, S. C., Myint, P. K., Hold, G. L.
    BMC Medical Education, vol. 17, 245
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Reduction in colposcopy workload and associated clinical activity following HPV catch-up vaccination programme in Scotland: an ecological study

    Cruickshank, M. E., Pan, J., Cotton, S. C., Kavanagh, K., Robertson, C., Cuschieri, K., Cubie, H., Palmer, T., Pollock, K. G.
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 124, no. 9, pp. 1386-1393
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
    • [OPEN ACCESS]

  • The impact of HPV type on colposcopy performance in women offered HPV immunisation in a catch-up vaccine programme: a two centre observational study

    Munro, A., Gillespie, C., Cotton, S., Busby-Earle, C., Kavanagh, K., Cuschieri, K., Cubie, H., Robertson, C., Smart, L., Pollock, K., Moore, C., Palmer, T., Cruickshank, M. E.
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 124, no. 9, pp. 1394-1401
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]
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    • [OPEN ACCESS]

  • Psychosocial morbidity in women with abnormal cervical cytology managed by cytological surveillance or initial colposcopy: longitudinal analysis from the TOMBOLA randomised trial

    Fielding, S., Rothnie, K., Gray, N. M., Little, J., Cruickshank, M., Neal, K., Walker, L., Whynes, D., Cotton, S., Sharp, L.
    Psycho-Oncology, vol. 26, no. 4, pp. 476–483
    Contributions to Journals: Articles
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    • [OPEN ACCESS]
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  • An Open-Label Investigation of the Pharmacokinetics and Tolerability of Oral Cysteamine in Adults with Cystic Fibrosis

    Devereux, G., Steele, S., Griffiths, K., Devlin, E., Fraser-Pitt, D., Cotton, S., Norrie, J., Chrystyn, H., O'Neil, D.
    Clinical Drug Investigation, vol. 36, no. 8, pp. 605-612
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • HPV immunisation and cervical screening - confirmation of changed performance of cytology as a screening test in immunised women: a retrospective population based cohort study

    Palmer, T. J., McFadden, M., Pollock, K. G. J., Kavanagh, K., Cuschieri, K., Cruickshank, M., Cotton, S., Nicoll, S., Robertson, C.
    British Journal of Cancer, vol. 114, no. 5, pp. 582-589
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Behavioural recovery after treatment for varicose veins

    Cotton, S. C., MacLennan, G., Brittenden, J., Prior, M., Francis, J.
    British Journal of Surgery, vol. 103, no. 4, pp. 374-381
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Impact of post-colposcopy management on women's long-term worries: results from the UK population-based TOMBOLA trial

    Sharp, L., Cotton, S., Cruickshank, M., Gray, N., Smart, L., Whynes, D., Little, J., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    Journal of Family Planning and Reproductive Health Care, vol. 42, no. 1, pp. 43-51
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Decision aids for people considering taking part in clinical trials

    Gillies, K., Cotton, S. C., Brehaut, J. C., Politi, M. C., Skea, Z.
    Cochrane Database of Systematic Reviews, no. 11, CD009736
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Long-term Worries after Colposcopy: Which Women Are at Increased Risk?

    Sharp, L., Cotton, S. C., Cruickshank, M. E., Gray, N. M., Neal, K., Rothnie, K., Thornton, A. J., Walker, L. G., Little, J., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    Women's Health Issues, vol. 25, no. 5, pp. 517-527
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • SMS text pre-notification and delivery of reminder e-mails to increase response rates to postal questionnaires in the SUSPEND trial: a factorial design, randomised controlled trial

    Starr, K., McPherson, G., Forrest, M., Cotton, S. C.
    Trials, vol. 16, 295
    Contributions to Journals: Articles
    • [ONLINE] DOI:
    • [OPEN ACCESS]

  • Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial

    Devereux, G., Cotton, S., Barnes, P., Briggs, A., Burns, G., Chaudhuri, R., Chrystyn, H., Davies, L., De Soyza, A., Fielding, S., Gompertz, S., Haughney, J. A. F., Lee, A. J., McCormack, K., McPherson, G., Morice, A., Norrie, J., Sullivan, A., Wilson, A., Price, D.
    Trials, vol. 16, 267
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • Making randomised trials more efficient: report of the first meeting to discuss the Trial Forge platform

    Treweek, S., Altman, D. G., Bower, P., Campbell, M., Chalmers, I., Cotton, S., Craig, P., Crosby, D., Davidson, P., Devane, D., Duley, L., Dunn, J., Elbourne, D., Farrell, B., Gamble, C., Gillies, K., Hood, K., Lang, T., Littleford, R., Loudon, K., McDonald, A., McPherson, G., Nelson, A., Norrie, J., Ramsay, C., Sandercock, P., Shanahan, D. R., Summerskill, W., Sydes, M., Williamson, P., Clarke, M.
    Trials, vol. 16, 261
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • A normal colposcopy examination fails to provide psychological reassurance for women who have had low-grade abnormal cervical cytology

    Cotton, S. C., Sharp, L., Little, J., Gray, N. M., Walker, L. G., Whynes, D. K., Cruickshank, M. E., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    Cytopathology, vol. 26, no. 3, pp. 178-187
    Contributions to Journals: Articles
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  • Clinical effectiveness and cost-effectiveness of foam sclerotherapy, endovenous laser ablation and surgery for varicose veins: results from the Comparison of LAser, Surgery and foam Sclerotherapy (CLASS) randomised controlled trial

    Brittenden, J., Cotton, S. C., Elders, A., Tassie, E., Scotland, G., Ramsay, C. R., Norrie, J., Burr, J., Francis, J., Wileman, S., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., MacLennan, G., Prior, M., Bolsover, D., Campbell, M. K.
    Health Technology Assessment, vol. 19, no. 27, pp. 1-342
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • Management of women with low grade cytology: how reassuring is a normal colposcopy examination?

    Cruickshank, M. E., Cotton, S. C., Sharp, L., Smart, L., Walker, L. G., Little, J., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    BJOG-An International Journal of Obstetrics and Gynaecology, vol. 122, no. 3, pp. 380-386
    Contributions to Journals: Articles
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  • Normative data for the Hospital Anxiety and Depression Scale

    Breeman, S., Cotton, S., Fielding, S., Jones, G. T.
    Quality of Life Research, vol. 24, no. 2, pp. 391-398
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • Measuring the psychosocial burden in women with low-grade abnormal cervical cytology in the TOMBOLA trial: psychometric properties of the Process and Outcome Specific Measure (POSM)

    Rothnie, K., Cotton, S. C., Fielding, S., Gray, N. M., Little, J., Cruickshank, M. E., Walker, L. G., Avis, M., Sharp, L.
    Health and Quality of Life Outcomes, vol. 12, 154
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • Cost-effectiveness of ultrasound-guided foam sclerotherapy, endovenous laser ablation or surgery as treatment for primary varicose veins from the randomized CLASS trial

    Tassie, E., Scotland, G., Brittenden, J., Cotton, S. C., Elders, A., Campbell, M. K., Campbell, B., Gough, M., Burr, J. M., Ramsay, C. R., CLASS Study Team
    British Journal of Surgery, vol. 101, no. 12, pp. 1532-1540
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • A randomized trial comparing treatments for varicose veins

    Brittenden, J., Cotton, S. C., Elders, A., Ramsay, C. R., Norrie, J., Burr, J., Campbell, B., Bachoo, P., Chetter, I., Gough, M., Earnshaw, J., Lees, T., Scott, J., Baker, S. A., Francis, J., Tassie, E., Scotland, G., Wileman, S., Campbell, M. K.
    The New England Journal of Medicine, vol. 371, no. 13, pp. 1218-1227
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI)

    Siddiqi, N., Neil, C., Bruce, M., Maclennan, G., Cotton, S. C., Papadopoulou, S., Feelisch, M., Bunce, N., Lim, P. O., Hildick-Smith, D., Horowitz, J., Madhani, M., Boon, N., Dawson, D., Kaski, J. C., Frenneaux, M., NIAMI investigators
    European Heart Journal, vol. 35, no. 19, pp. 1255-1262
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • The unintended consequences of cervical screening: distress in women undergoing cytologic surveillance

    Sharp, L., Cotton, S., Cruickshank, M., Gray, N. M., Harrild, K., Smart, L., Walker, L. G., Little, J., The TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) Group
    Journal of Lower Genital Tract Disease, vol. 18, no. 2, pp. 142-150
    Contributions to Journals: Articles
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  • Patient information leaflets (PILs) for UK randomised controlled trials: a feasibility study exploring whether they contain information to support decision making about trial participation

    Gillies, K., Huang, W., Skea, Z., Brehaut, J., Cotton, S.
    Trials, vol. 15, 62
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • Nitrites in Acute Myocardial Infarction

    Siddiqi, N., Bruce, M., Neil, C. J., MacLennan, G., Cotton, S., Papadopoulou, S. A., Jagpal, B., Brown, S., Gonzalez, F. P., Singh, S., Schwarz, K., Feelisch, M., Bunce, N., Lim, P. O., Hildick-Smith, D., Horowitz, J., Madhani, M., Boon, N., Dawson, D., Kaski, J., Frenneaux, M. P.
    Circulation, vol. 128, no. 24, pp. 2705
    Contributions to Journals: Abstracts

  • Impact of alternative management policies on health-related quality of life in women with low-grade abnormal cervical cytology referred for colposcopy

    Whynes, D. K., Sharp, L., Cotton, S. C., Cruickshank, M., Gray, N. M., Little, J., Waugh, N.
    European Journal of Obstetrics & Gynecology and Reproductive Biology, vol. 169, no. 1, pp. 88-92
    Contributions to Journals: Articles
    • [ONLINE] DOI:

  • Clinical and economic evaluation of laparoscopic surgery compared with medical management for gastro-oesophageal reflux disease: 5-year follow-up of multicentre randomised trial (the REFLUX trial)

    Grant, A. M., Boachie, C., Cotton, S. C., Faria, R., Bojke, L., Epstein, D. M., Ramsay, C. R., Corbacho, B., Sculpher, M., Krukowski, Z. H., Heading, R. C., Campbell, M. K.
    Health Technology Assessment, vol. 17, no. 22, pp. 1-166
    Contributions to Journals: Articles
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    • [OPEN ACCESS]

  • Protocol: does sodium nitrite administration reduce ischaemia-reperfusion injury in patients presenting with acute ST segment elevation myocardial infarction? Nitrites in acute myocardial infarction (NIAMI)

    Siddiqi, N., Bruce, M., Neil, C. J., Jagpal, B., MacLennan, G. S., Cotton, S. C., Papadopoulo, S. A., Bunce, N., Lim, P., Schwarz, K., Singh, S., Hildick-Smith, D., Horowitz, J. D., Madhani, M., Boon, N., Kaski, J., Dawson, D., Frenneaux, M. P.
    Journal of translational medicine, vol. 11, 116
    Contributions to Journals: Articles
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  • Minimal access surgery compared with medical management for gastro-oesophageal reflux disease: five year follow-up of a randomised controlled trial (REFLUX)

    Grant, A. M., Cotton, S. C., Boachie, C., Ramsay, C. R., Krukowski, Z. H., Heading, R. C., Campbell, M. K., REFLUX Trial Group
    BMJ, vol. 346, f1908
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